EP 0847395 A1 19980617 - PYRROLYL TETRAHYDROQUINOXALIN DIONES, THEIR PRODUCTION AND USE IN THE TREATMENT OF DISEASES
Title (en)
PYRROLYL TETRAHYDROQUINOXALIN DIONES, THEIR PRODUCTION AND USE IN THE TREATMENT OF DISEASES
Title (de)
PYRROLYL-TETRAHYDROCHINOXALINDIONE, IHRE HERSTELLUNG UND VERWENDUNG ZUR BEKÄMPFUNG VON KRANKHEITEN
Title (fr)
PYRROLYLE-TETRAHYDROQUINOXALINEDIONES, LEUR PREPARATION ET LEUR UTILISATION POUR LUTTER CONTRE LES MALADIES
Publication
Application
Priority
- DE 19532050 A 19950831
- EP 9603759 W 19960826
Abstract (en)
[origin: DE19532050A1] Pyrrolyl tetrahydroquinoxalin diones of formula (I) and their tautomeric and isomeric forms, and their physiologically acceptable salts, in which the variables are: R<1> - hydrogène, cyclohexyl radical, an aliphatic radical with 1 to 4 atoms which can bear the radical COOR<5>, where R<5> is hydrogen or C1-C4 alkyl, R<2> -COOH, -COO-C1-C4, -COO-(CH2)m-Ph, -CONR<6>R<7> and (a), where m may be a whole number from 1 to 6, R<6> is hydrogen, -C1-C4 alkyl or OH and R<7> is hydrogen, -C1-C4 alkyl, -(CH2)m-Ph or (b), where all the phenyl or pyridyl rings contained in R<2> may be substituted by up to 3 of the following radicals: -C1-C4 alkyl, halogen, -O-C1-C4 alkyl, -OCF3, -NO2, -CN, -COOR<5> or -CONHR<5>; R<3> is -CF3, -NO2, -CN and R<4> is hydrogen; or R<3> and R<4> together may be an anellated benzole ring. The compounds are suitable as medicaments in human and veterinary medicine.
IPC 1-7
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/495 (2006.01); A61K 31/498 (2006.01); A61P 25/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01)
CPC (source: EP US)
A61P 25/04 (2017.12 - EP); C07D 401/14 (2013.01 - EP US); C07D 403/04 (2013.01 - EP US)
Citation (search report)
See references of WO 9708168A1
Designated contracting state (EPC)
CH DE FR GB IT LI NL
DOCDB simple family (publication)
DE 19532050 A1 19970306; AU 6984696 A 19970319; CN 1092192 C 20021009; CN 1194643 A 19980930; EP 0847395 A1 19980617; JP H11511451 A 19991005; US 6407109 B1 20020618; WO 9708168 A1 19970306
DOCDB simple family (application)
DE 19532050 A 19950831; AU 6984696 A 19960826; CN 96196618 A 19960826; EP 9603759 W 19960826; EP 96930966 A 19960826; JP 50984797 A 19960826; US 27798 A 19980127