EP 0851760 A4 19981125 - INTERLEUKIN CONVERTING ENZYME AND APOPTOSIS
Title (en)
INTERLEUKIN CONVERTING ENZYME AND APOPTOSIS
Title (de)
INTERLEUKIN UMWANDELNDES ENZYM UND APOPTOSE
Title (fr)
ENZYME DE CONVERSION D'INTERLEUKINES ET APOPTOSE
Publication
Application
Priority
- US 9613867 W 19960829
- US 308395 P 19950831
Abstract (en)
[origin: WO9707805A1] The present invention is to the novel compounds of Formula (I), their pharmaceutical compositions, and to the novel inhibition of ICE and ICE-like proteins for use in the treatment of apoptosis, and disease states caused by excessive or inappropriate cell death.
IPC 1-7
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/545 (2006.01); A61K 31/546 (2006.01); A61P 1/00 (2006.01); A61P 1/16 (2006.01); A61P 19/00 (2006.01); A61P 19/02 (2006.01); A61P 19/10 (2006.01); A61P 43/00 (2006.01); C07D 501/00 (2006.01)
CPC (source: EP)
A61P 1/00 (2017.12); A61P 1/16 (2017.12); A61P 19/00 (2017.12); A61P 19/02 (2017.12); A61P 19/10 (2017.12); A61P 43/00 (2017.12); C07D 501/00 (2013.01)
Citation (search report)
- [X] WO 9502603 A2 19950126 - PHARMACIA SPA [IT], et al
- [X] EP 0124081 A2 19841107 - MERCK & CO INC [US]
- [X] EP 0267723 A2 19880518 - MERCK & CO INC [US]
- [X] P. E. FINKE ET AL.: "Inhibition of Human Leukocyte Elastase. 4. Selection of a Substituted Cephalosporin (L-658,758) as a Topical Aerosol", J. MED. CHEM., vol. 35, no. 21, 1992, pages 3731 - 3744, XP002077983
- [X] M. ALPEGIANI ET AL.: "Cephem Sulfones as Inactivators of Human Leukocyte Elastase. 5. 7-alpha-Methoxy- and 7-alpha-Chloro-1,1-dioxocephem 4-Ketones", J. MED. CHEM., vol. 37, no. 23, 1994, pages 4003 - 4019, XP002077984
- See references of WO 9707805A1
Designated contracting state (EPC)
BE CH DE ES FR GB IT LI NL
DOCDB simple family (publication)
WO 9707805 A1 19970306; EP 0851760 A1 19980708; EP 0851760 A4 19981125; JP H11514345 A 19991207
DOCDB simple family (application)
US 9613867 W 19960829; EP 96930620 A 19960829; JP 51055397 A 19960829