EP 0851925 B1 20050803 - HUMAN GROWTH HORMONE VARIANTS
Title (en)
HUMAN GROWTH HORMONE VARIANTS
Title (de)
VARIANTEN DES MENSCHLICHEN WACHSTUMSHORMONS
Title (fr)
VARIANTS DE L'HORMONE DE CROISSANCE HUMAINE
Publication
Application
Priority
- US 9614830 W 19960920
- US 53706795 A 19950921
- US 53706895 A 19950921
Abstract (en)
[origin: EP1568772A2] Human growth hormone variants are disclosed having enhanced affinity for the growth hormone receptor. Also disclosed are human growth hormone variants conjugated to one or more chemical groups, such as poly(ethylene glycol), which is believed to prolong the in vivo half-life of the variants.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/00 (2006.01); A61K 38/00 (2006.01); A61K 38/27 (2006.01); A61K 47/48 (2006.01); A61P 3/00 (2006.01); A61P 3/10 (2006.01); A61P 5/00 (2006.01); A61P 5/08 (2006.01); A61P 5/12 (2006.01); A61P 13/12 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); A61P 43/00 (2006.01); C07K 1/107 (2006.01); C07K 14/61 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/18 (2006.01); C12N 15/63 (2006.01); C12P 21/02 (2006.01); C12R 1/19 (2006.01)
CPC (source: EP US)
A61K 47/60 (2017.08 - EP US); A61P 3/00 (2018.01 - EP); A61P 3/10 (2018.01 - EP); A61P 5/00 (2018.01 - EP); A61P 5/06 (2018.01 - EP); A61P 5/08 (2018.01 - EP); A61P 5/12 (2018.01 - EP); A61P 13/12 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 37/00 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 14/61 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); C07K 2319/00 (2013.01 - EP US); Y10S 930/12 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9711178 A1 19970327; AT E301196 T1 20050815; AT E455171 T1 20100115; AU 7073396 A 19970409; AU 718439 B2 20000413; CA 2230492 A1 19970327; CA 2230492 C 20090526; CA 2658039 A1 19970327; DE 122006000003 I1 20060504; DE 122006000003 I2 20110113; DE 69635026 D1 20050908; DE 69635026 T2 20060524; DE 69638117 D1 20100304; DE 851925 T1 20030814; DK 0851925 T3 20051128; DK 1568772 T3 20101018; EP 0851925 A1 19980708; EP 0851925 B1 20050803; EP 1568771 A2 20050831; EP 1568771 A3 20060517; EP 1568772 A2 20050831; EP 1568772 A3 20060517; EP 1568772 B1 20100113; ES 2190388 T1 20030801; ES 2190388 T3 20060401; ES 2338431 T3 20100507; HK 1012508 A1 19990806; JP 2005021157 A 20050127; JP 3628333 B2 20050309; JP 3693668 B2 20050907; JP H11512298 A 19991026; LU 91204 I2 20060206; NL 300210 I1 20060201; NL 300210 I2 20070501; PT 1568772 E 20100414; US 5849535 A 19981215; US 6004931 A 19991221; US 6057292 A 20000502; US 6136563 A 20001024
DOCDB simple family (application)
US 9614830 W 19960920; AT 05007536 T 19960920; AT 96931597 T 19960920; AU 7073396 A 19960920; CA 2230492 A 19960920; CA 2658039 A 19960920; DE 122006000003 C 19960920; DE 69635026 C 19960920; DE 69635026 T 19960920; DE 69638117 T 19960920; DE 96931597 T 19960920; DK 05007536 T 19960920; DK 96931597 T 19960920; EP 05007535 A 19960920; EP 05007536 A 19960920; EP 96931597 A 19960920; ES 05007536 T 19960920; ES 96931597 T 19960920; HK 98113801 A 19981217; JP 2004126082 A 20040421; JP 51281497 A 19960920; LU 91204 C 20051028; NL 300210 C 20051130; PT 05007536 T 19960920; US 2858798 A 19980224; US 2864898 A 19980224; US 2865298 A 19980224; US 71739496 A 19960920