EP 0852493 A1 19980715 - TRANSDERMAL MATRIX SYSTEM
Title (en)
TRANSDERMAL MATRIX SYSTEM
Title (de)
TRANSDERMALES MATRIXSYSTEM
Title (fr)
SYSTEME MATRICIEL TRANSDERMIQUE
Publication
Application
Priority
- FR 9601496 W 19960925
- FR 9511325 A 19950927
Abstract (en)
[origin: WO9711689A1] A novel transdermal system for the percutaneous delivery of a hormone, including a carrier and an adhesive matrix, is disclosed. The matrix includes (a) 20-50 parts by weight of a poly(styrene-isoprene-styrene) triblock copolymer, (b) 30-60 parts by weight of a tackifier resin, (c) 4-25 parts by weight of propylene glycol laurate, (d) 2-10 parts by weight of a compound selected from N-alkyl-2-pyrrolidones, wherein the alkyl group is a C4-15 group, (e) 0.01-2 parts by weight of a stabilising agent, (f) 0.1-12 parts by weight of at least one hormone selected from the group consisting of oestrogenic and progestogenic components, and (g) 1-12 parts by weight of a vinyl acetate/N-vinyl-2-pyrrolidone copolymer. A method for preparing said system and the therapeutical use thereof are also disclosed.
IPC 1-7
IPC 8 full level
A61K 9/70 (2006.01); A61K 38/24 (2006.01)
CPC (source: EP US)
A61K 9/7053 (2013.01 - EP US); A61K 9/7076 (2013.01 - EP US)
Citation (search report)
See references of WO 9711689A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9711689 A1 19970403; AU 7135196 A 19970417; CA 2233171 A1 19970403; CN 1197389 A 19981028; EP 0852493 A1 19980715; FR 2739031 A1 19970328; FR 2739031 B1 19971121; JP H11514989 A 19991221; NO 981315 D0 19980323; NO 981315 L 19980324; US 6007835 A 19991228
DOCDB simple family (application)
FR 9601496 W 19960925; AU 7135196 A 19960925; CA 2233171 A 19960925; CN 96197186 A 19960925; EP 96932649 A 19960925; FR 9511325 A 19950927; JP 51318397 A 19960925; NO 981315 A 19980323; US 4372698 A 19980326