EP 0856010 A1 19980805 - MAMMAGLOBIN, ANTIBODIES THERETO, AND THEIR USE FOR DETECTING DISEASES OF THE BREAST
Title (en)
MAMMAGLOBIN, ANTIBODIES THERETO, AND THEIR USE FOR DETECTING DISEASES OF THE BREAST
Title (de)
MAMMAGLOBIN, ANTIKÖRPER HIERZU UND HRE VERWENDUNG ZUR DETEKTION VON BRUSTERKRANKUNGEN
Title (fr)
MAMMOGLOBINES, ANTICORPS CONTRE CELLES-CI ET LEUR UTILISATION POUR LA DETECTION DES MALADIES DU SEIN
Publication
Application
Priority
- US 9714666 W 19970819
- US 69710696 A 19960819
Abstract (en)
[origin: WO9807753A1] A set of contiguous and partially overlapping RNA sequences and polypeptides encoded thereby, designated as mammaglobin and transcribed from breast tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the breast such as breast cancer. Also provided are antibodies which specifically bind to mammaglobin-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific mammaglobin polypeptide, which molecules are useful for the therapeutic treatment of breast diseases, tumors or metastases.
IPC 1-7
C07K 16/18; G01N 33/577; G01N 33/68; G01N 33/543; G01N 33/574; A61K 39/00; A61K 31/70
IPC 8 full level
C07K 14/47 (2006.01); C07K 16/18 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP)
C07K 14/47 (2013.01); C07K 16/18 (2013.01); A61K 39/00 (2013.01); A61K 2039/51 (2013.01); C07K 2319/00 (2013.01)
Designated contracting state (EPC)
AT BE CH DE ES FR GB IT LI NL
DOCDB simple family (publication)
DOCDB simple family (application)
US 9714666 W 19970819; EP 97938468 A 19970819