EP 0856062 A2 19980805 - HERPESVIRUS VECTORS AND THEIR USES
Title (en)
HERPESVIRUS VECTORS AND THEIR USES
Title (de)
HERPESVIRUS-VEKTOREN UND DEREN VERWENDUNG
Title (fr)
VECTEURS DU VIRUS HERPETIQUE ET LEURS UTILISATIONS
Publication
Application
Priority
- GB 9602576 W 19961021
- GB 9525906 A 19951219
- US 564995 P 19951019
Abstract (en)
[origin: WO9714808A2] A process of treating a human or non-human animal cell to introduce heterologous genetic material into said cell and express said material in said cell, comprises (a) providing a recombinant herpesviral vector which is an attenuated or replication-defective and non-transforming mutant herpesvirus, and which carries heterologous genetic material, and (b) transducing human or non-human animal cells selected from: haematopoietic cells, malignant cells related to blood cells, and malignant or non-malignant CD34+ cells; by contacting said cells with said virus vector to transduce said cells and express said genetic material. Among applications of the technique is modification of haematopoietic cells by transfer of genes, e.g. to generate tumour immunogens from malignant cells.
IPC 1-7
IPC 8 full level
A61K 31/00 (2006.01); A61K 38/19 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/52 (2006.01); C07K 14/535 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C12N 15/869 (2006.01)
CPC (source: EP)
A61K 35/28 (2013.01); A61P 35/00 (2017.12); C07K 14/535 (2013.01); C12N 15/86 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C12N 2710/16643 (2013.01)
Citation (search report)
See references of WO 9714808A2
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9714808 A2 19970424; WO 9714808 A3 19970724; CA 2234877 A1 19970424; EP 0856062 A2 19980805; JP H11513565 A 19991124; MX 9802999 A 19980930
DOCDB simple family (application)
GB 9602576 W 19961021; CA 2234877 A 19961021; EP 96935051 A 19961021; JP 51563197 A 19961021; MX 9802999 A 19980416