EP 0857209 A1 19980812 - FIBROBLAST GROWTH FACTOR 13
Title (en)
FIBROBLAST GROWTH FACTOR 13
Title (de)
FIBROBLASTENWACHSTUMSFAKTOR 13
Title (fr)
FACTEUR DE CROISSANCE DES FIBROBLASTES 13
Publication
Application
Priority
US 9507108 W 19950605
Abstract (en)
[origin: WO9639508A1] Disclosed is a human Fibroblast growth factor-13 polypeptide and DNA (RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques. Also disclosed are methods for utilizing such polypeptide for promoting wound healing for example as a result of burns and ulcers, to prevent neuronal damage associated with stroke and due to neuronal disorders and promote neuronal growth, and to prevent skin aging and hair loss, to stimulate angiogenesis, mesodermal induction in early embryos and limb regeneration. Antagonists against such polypeptides and their use as a therapeutic to prevent abnormal cellular proliferation, hyper-vascular diseases and epithelial lens cell proliferation are also disclosed. Diagnostic methods for detecting mutations in the coding sequence and alterations in the concentration of the polypeptides in a sample derived from a host are also disclosed.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); C07K 14/50 (2006.01); C07K 16/22 (2006.01); C12N 5/10 (2006.01); C12N 15/12 (2006.01); C12P 21/08 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP KR)
C07K 14/50 (2013.01 - EP KR); C12N 15/11 (2013.01 - KR); A61K 38/00 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9639508 A1 19961212; AU 2697995 A 19961224; AU 702682 B2 19990304; EP 0857209 A1 19980812; EP 0857209 A4 19980812; JP H11507504 A 19990706; KR 19990022315 A 19990325
DOCDB simple family (application)
US 9507108 W 19950605; AU 2697995 A 19950605; EP 95922214 A 19950605; JP 50036197 A 19950605; KR 19970708795 A 19971204