EP 0861234 A1 19980902 - ENANTIOMERS OF CIS-BENZ E INDOLE COMPOUNDS, THEIR PREPARATION AND UTILITY AS DOPAMINE-D3 RECEPTOR SELECTIVE AGENTS
Title (en)
ENANTIOMERS OF CIS-BENZ E INDOLE COMPOUNDS, THEIR PREPARATION AND UTILITY AS DOPAMINE-D3 RECEPTOR SELECTIVE AGENTS
Title (de)
ENANTIOMERE VON CIS-BENZ(E)INDOL-VERBINDUNGEN, DEREN HERSTELLUNG UND VERWENDUNG ALS FÜR DEN DOPAMIN-D3-REZEPTOR SELEKTIVE AGENZIEN
Title (fr)
ENANTIOMERES DE COMPOSES DE CIS-BENZ E INDOLE, LEUR PREPARATION ET UTILITE EN TANT QU'AGENTS SELECTIFS DU RECEPTEUR DE LA DOPAMINE-D3
Publication
Application
Priority
- DK 9600464 W 19961108
- DK 126195 A 19951110
Abstract (en)
[origin: WO9717326A1] Enantiomers of cis-Benz[e]indole compounds of formula (I), wherein R1 is hydrogen, C1-6-alkyl, cycloalkylmethyl, allyl or alkenyl; R<4> is hydroxy, C1-6-alkoxy, O-acyl, triflate or carbamoyl; and R<2>, R<3>, R<5> are the same or different and independently are hydrogen, halogen, trifluoromethyl or C1-6-alkyl, are useful as selective dopamine-D3 receptor ligands in the treatment of central nervous system ailments related to dysfunction of the central dopamine system.
IPC 1-7
IPC 8 full level
A61K 31/40 (2006.01); A61K 31/00 (2006.01); A61K 31/403 (2006.01); A61P 25/04 (2006.01); A61P 43/00 (2006.01); C07D 209/60 (2006.01)
CPC (source: EP)
A61P 25/04 (2017.12); A61P 43/00 (2017.12); C07D 209/60 (2013.01)
Citation (search report)
See references of WO 9717326A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated extension state (EPC)
LT LV SI
DOCDB simple family (publication)
WO 9717326 A1 19970515; AU 7490496 A 19970529; EP 0861234 A1 19980902; JP H11515030 A 19991221
DOCDB simple family (application)
DK 9600464 W 19961108; AU 7490496 A 19961108; EP 96937197 A 19961108; JP 51776797 A 19961108