Global Patent Index - EP 0862435 A1

EP 0862435 A1 19980909 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

INHIBITOREN DER FARNESYL-PROTEIN-TRANSFERASE

Title (fr)

INHIBITEURS DE LA FARNESYL-PROTEINE TRANSFERASE

Publication

EP 0862435 A1 19980909 (EN)

Application

EP 96942798 A 19961118

Priority

  • GB 9604311 A 19960229
  • US 9618811 W 19961118
  • US 749895 P 19951122

Abstract (en)

[origin: WO9718813A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7

A61K 31/445; C07D 401/12

IPC 8 full level

A61K 31/00 (2006.01); A61K 31/4427 (2006.01); A61K 31/445 (2006.01); A61K 31/4465 (2006.01); A61K 31/4523 (2006.01); A61K 31/454 (2006.01); A61K 31/535 (2006.01); A61K 31/5375 (2006.01); A61K 31/5377 (2006.01); A61P 9/00 (2006.01); A61P 13/00 (2006.01); A61P 13/12 (2006.01); A61P 27/00 (2006.01); A61P 27/02 (2006.01); A61P 31/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 233/24 (2006.01); C07D 401/12 (2006.01)

CPC (source: EP)

A61P 9/00 (2017.12); A61P 13/00 (2017.12); A61P 13/12 (2017.12); A61P 27/00 (2017.12); A61P 27/02 (2017.12); A61P 31/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 233/24 (2013.01); C07D 401/12 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9718813 A1 19970529; AU 1162697 A 19970611; AU 704139 B2 19990415; CA 2238081 A1 19970529; EP 0862435 A1 19980909; EP 0862435 A4 19990203; JP 2000500502 A 20000118

DOCDB simple family (application)

US 9618811 W 19961118; AU 1162697 A 19961118; CA 2238081 A 19961118; EP 96942798 A 19961118; JP 51994197 A 19961118