EP 0862450 A2 19980909 - A METHOD FOR INHIBITING ATTACHMENT OF H. INFLUENZAE TO HUMAN CELLS USING PHOSPHORYLATED RECOMBINANT HUMAN BETA-CASEIN
Title (en)
A METHOD FOR INHIBITING ATTACHMENT OF H. INFLUENZAE TO HUMAN CELLS USING PHOSPHORYLATED RECOMBINANT HUMAN BETA-CASEIN
Title (de)
VERFAHREN ZUR HEMMUNG DER ANHEFTUNG VON H.INFLUENZAE AN MENSCHLICHEN ZELLEN UNTER VERWENDUNG VON PHOSPHORYLIERTEM RECOMBINANT MENSCHLICHEN BETA-CASEIN
Title (fr)
PROCEDE PERMETTANT D'INHIBER LA FIXATION DE H. INFLUENZAE SUR DES CELLULES HUMAINES A L'AIDE DE BETA-CASEINE HUMAINE PHOSPHORYLEE DE RECOMBINAISON
Publication
Application
Priority
- US 9617860 W 19961106
- US 55252995 A 19951106
Abstract (en)
[origin: WO9717085A2] A method is provided for inhibiting the attachment of H. influenzae to human cells, such as pharyngeal cells, by contacting the bacilli with phosphorylated recombinant human beta -casein that have at least 3 phosphate groups. A product containing phosphorylated recombinant human beta -casein may be a liquid enteral nutritional product such as infant formula. The enteral nutritional product may be used for the prevention and treatment of otitis media in infants. The phosphorylated recombinant human beta -casein may also be administered as a throat spray or used in nose drops or a spray.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A23L 1/305 (2006.01); A61K 31/00 (2006.01); A61K 38/00 (2006.01); A61P 27/00 (2006.01); A61P 27/16 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); C07K 14/47 (2006.01)
CPC (source: EP)
A23L 33/19 (2016.07); A61P 27/00 (2017.12); A61P 27/16 (2017.12); A61P 31/00 (2017.12); A61P 31/04 (2017.12); C07K 14/4732 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9717085A2
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9717085 A2 19970515; WO 9717085 A3 19970807; AU 7610496 A 19970529; EP 0862450 A2 19980909; JP 2000500141 A 20000111; MX 9803565 A 19980930; NZ 322369 A 19991129
DOCDB simple family (application)
US 9617860 W 19961106; AU 7610496 A 19961106; EP 96938817 A 19961106; JP 51832197 A 19961106; MX 9803565 A 19980506; NZ 32236996 A 19961106