EP 0862620 A1 19980909 - TYROSINE KINASE GENE AND GENE PRODUCT
Title (en)
TYROSINE KINASE GENE AND GENE PRODUCT
Title (de)
TYROSINKINASE UND DAS DAFÜR KODIERENDE GEN
Title (fr)
GENE DE LA TYROSINE KINASE ET PRODUIT GENIQUE ASSOCIE
Publication
Application
Priority
- US 9616359 W 19961011
- US 528695 P 19951012
Abstract (en)
[origin: WO9713846A1] A human intracellular tyrosine kinase polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide to suppress the transforming activity of certain genes by acting in a regulatory role, to regulate changes in the proliferation and differentiation status of cells, namely, hematopoietic stem cells for bone marrow transplantation and support for cancer therapy. Diagnostic assays for identifying mutations in nucleic acid sequences encoding a polypeptide of the present invention for detecting diseases, for example, cancer, are also disclosed.
IPC 1-7
IPC 8 full level
C12N 9/12 (2006.01); C12N 15/12 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C12N 9/1205 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9713846A1
Designated contracting state (EPC)
CH DE FR GB IT LI NL
DOCDB simple family (publication)
WO 9713846 A1 19970417; AU 7442396 A 19970430; EP 0862620 A1 19980909
DOCDB simple family (application)
US 9616359 W 19961011; AU 7442396 A 19961011; EP 96936414 A 19961011