Global Patent Index - EP 0863900 A1

EP 0863900 A1 19980916 - PROCESS FOR THE PREPARATION OF A GROWTH HORMONE SECRETAGOGUE

Title (en)

PROCESS FOR THE PREPARATION OF A GROWTH HORMONE SECRETAGOGUE

Title (de)

VERFAHREN ZUR HERSTELLUNG VON EINER WACHSBUMSHORMON-SEKRETION BEFÖRDERENDEN VERBINDUNG

Title (fr)

PROCEDE DE PREPARATION D'UN FACTEUR DE SECRETION D'HORMONE DE CROISSANCE

Publication

EP 0863900 A1 19980916 (EN)

Application

EP 96936868 A 19961023

Priority

  • GB 9602949 A 19960213
  • US 9616954 W 19961023
  • US 589895 P 19951027

Abstract (en)

[origin: WO9715573A1] The present invention is directed to a novel process for the preparation of the compound N-[1(R)-[(1,2-dihydro-1-methanesulfonyl-spiro[3H-indole-3,4'-piperdin]-1'-yl)carbonyl]-2-(phenylmethyl-oxy)ethyl]-2-amino-2-methyl-propanamide, and salts thereof, which has structure (1) and which has the ability to stimulate the release of natural or endogenous growth hormone. This compound may be used to treat conditions which require the stimulation of growth hormone production or secretion such as in humans with a deficiency of natural growth hormone or in animals used for food or wool production where the stimulation of growth hormone will result in a larger, more productive animal.

IPC 1-7

C07D 471/10; A61K 31/445

IPC 8 full level

C07D 471/10 (2006.01); C07K 5/06 (2006.01); C07K 5/062 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP KR)

A61K 38/00 (2013.01 - KR); C07D 471/10 (2013.01 - KR); C07K 5/06034 (2013.01 - EP KR); A61K 38/00 (2013.01 - EP)

Citation (search report)

See references of WO 9715573A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9715573 A1 19970501; AR 004124 A1 19980930; AU 7468596 A 19970515; BR 9610887 A 19990713; CA 2235511 A1 19970501; CZ 128298 A3 19980715; EP 0863900 A1 19980916; HR P960494 A2 19980430; HU P9902095 A2 19991028; HU P9902095 A3 20010528; JP H11513984 A 19991130; KR 19990067097 A 19990816; MX 9803316 A 19980930; PL 326428 A1 19980914; SK 51198 A3 19981104; YU 56596 A 19990927

DOCDB simple family (application)

US 9616954 W 19961023; AR P960104931 A 19961025; AU 7468596 A 19961023; BR 9610887 A 19961023; CA 2235511 A 19961023; CZ 128298 A 19961023; EP 96936868 A 19961023; HR P960494 A 19961025; HU P9902095 A 19961023; JP 51673697 A 19961023; KR 19980703037 A 19980427; MX 9803316 A 19980427; PL 32642896 A 19961023; SK 51198 A 19961023; YU 56596 A 19961025