Global Patent Index - EP 0866716 A4

EP 0866716 A4 20020502 - METHODS OF TREATING DISORDERS OF NON-VISUAL SENSORY EPITHELIA

Title (en)

METHODS OF TREATING DISORDERS OF NON-VISUAL SENSORY EPITHELIA

Title (de)

VERFAHREN ZUR BEHANDLUNG VON STÖRUNGEN DES NICHTVISUELLEN SENSORISCHEN EPITHELS

Title (fr)

PROCEDES DE TRAITEMENT DE TROUBLES DANS DES EPITHELIUMS SENSORIELS NON VISUELS

Publication

EP 0866716 A4 20020502 (EN)

Application

EP 96940360 A 19961112

Priority

  • US 9618031 W 19961112
  • US 654195 P 19951113

Abstract (en)

[origin: WO9717983A1] In general, the present invention provides methods for promoting the function of inner ear cells using neuregulins. A novel aspect of the invention involves the use of neuregulins as growth factors to promote function of non-visual sensory epithelial cells. Trteating of the non-visual sensory epithelial cells to provide these effects may be achieved by contacting non-visual sensory epithelial cells with a polypeptide described herein. The treatments may be provided to slow or halt net cell loss or to increase the amount or quality of non-visual sensory epithelial tissue present in the vertebrate.

IPC 1-7

A61K 38/00; A61K 38/18; A61K 31/70

IPC 8 full level

C12N 15/09 (2006.01); A61K 31/00 (2006.01); A61K 38/18 (2006.01); A61K 38/22 (2006.01); A61K 48/00 (2006.01); A61P 17/00 (2006.01); A61P 27/00 (2006.01); A61P 27/16 (2006.01); A61P 31/00 (2006.01); A61P 37/00 (2006.01); C12N 5/0793 (2010.01)

CPC (source: EP)

A61K 38/185 (2013.01); A61P 17/00 (2017.12); A61P 27/00 (2017.12); A61P 27/16 (2017.12); A61P 31/00 (2017.12); A61P 37/00 (2017.12); C12N 5/062 (2013.01); C12N 2501/60 (2013.01)

Citation (search report)

  • [PX] WO 9615812 A1 19960530 - CAMBRIDGE NEUROSCIENCE INC [US], et al
  • [A] MARCHIONNI-MA ET AL.: "Glial growth factros are alternatively spliced erbB2 ligands expressed in the nervous system", NATURE, vol. 362, 25 March 1993 (1993-03-25), pages 312 - 318, XP002188342
  • [A] BIRCHMEIER-C ET AL.: "Factors controlling growth, motility, and morphogenesis of normal and malignant epithelial cells", INTERNATIONAL REVIEW OF CYTOLOGY, vol. 160, 1995, pages 221 - 266, XP001053100
  • [A] CARRAWAY KL. ET AL.: "Neuregulins and their receptors", CURRENT OPINION IN NEUROBIOLOGY, vol. 5, October 1995 (1995-10-01), pages 606 - 612, XP001052960
  • See references of WO 9717983A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9717983 A1 19970522; AU 727037 B2 20001130; AU 7725896 A 19970605; EP 0866716 A1 19980930; EP 0866716 A4 20020502; JP 2000505781 A 20000516

DOCDB simple family (application)

US 9618031 W 19961112; AU 7725896 A 19961112; EP 96940360 A 19961112; JP 51896697 A 19961112