Global Patent Index - EP 0868178 A4

EP 0868178 A4 20000329 - ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE

Title (en)

ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE

Title (de)

ANTAGONISTEN DES GONADOTROPIN RELEASING HORMONS

Title (fr)

ANTAGONISTES DE LA GONADOLIBERINE

Publication

EP 0868178 A4 (EN)

Application

EP 96943763 A

Priority

  • GB 9603370 A
  • US 9620004 W
  • US 863295 P

Abstract (en)

[origin: WO9721435A1] There are disclosed compounds of formula (I) and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.

IPC 1-7

A61K 31/40; C07D 209/14

IPC 8 full level

C07D 401/06 (2006.01); A61K 31/40 (2006.01); A61K 31/403 (2006.01); A61K 31/404 (2006.01); A61K 31/4045 (2006.01); A61K 31/437 (2006.01); A61K 31/4427 (2006.01); A61K 31/4439 (2006.01); A61K 31/445 (2006.01); A61K 31/454 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); A61P 1/00 (2006.01); A61P 1/06 (2006.01); A61P 5/00 (2006.01); A61P 5/02 (2006.01); A61P 5/24 (2006.01); A61P 11/16 (2006.01); A61P 13/02 (2006.01); A61P 15/00 (2006.01); A61P 15/16 (2006.01); A61P 15/18 (2006.01); A61P 17/00 (2006.01); A61P 25/20 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); C07D 209/14 (2006.01); C07D 209/16 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 471/10 (2006.01)

CPC (source: EP)

A61P 1/00 (2018.01); A61P 1/06 (2018.01); A61P 5/00 (2018.01); A61P 5/02 (2018.01); A61P 5/24 (2018.01); A61P 11/16 (2018.01); A61P 13/02 (2018.01); A61P 15/00 (2018.01); A61P 15/16 (2018.01); A61P 15/18 (2018.01); A61P 17/00 (2018.01); A61P 25/20 (2018.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 209/16 (2013.01)

Citation (search report)

  • [XD] FR 2181559 A1 19731207 - AEC CHIMIE ORGANIQUE BIO [FR]
  • [A] EP 0348341 A2 19891227 - SCHERING AG [DE]
  • [AD] EP 0679642 A1 19951102 - TAKEDA CHEMICAL INDUSTRIES LTD [JP]
  • [E] WO 9721707 A1 19970619 - MERCK & CO INC [US], et al
  • [E] WO 9721704 A1 19970619 - MERCK & CO INC [US], et al
  • [E] WO 9721703 A1 19970619 - MERCK & CO INC [US], et al
  • [X] GARRATT, PETER J. ET AL: "Mapping the Melatonin Receptor. 3. Design and Synthesis of Melatonin Agonists and Antagonists Derived from 2-Phenyltryptamines", J. MED. CHEM. (1995), 38(7), 1132-9, XP002126976
  • [X] DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; RAO, RAVINDRA PRATAP: "Synthesis of some Mannich bases from 2-phenylindole and 5-nitro 2-phenylindole", XP002126977, retrieved from STN Database accession no. 71:91198 & LABDEV, PART A (1969), 7(2), 99-100
  • See also references of WO 9721435A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9721435 A1 19970619; AU 1291997 A 19970703; AU 704937 B2 19990506; CA 2240115 A1 19970619; EP 0868178 A1 19981007; EP 0868178 A4 20000329; JP 2001039871 A 20010213; JP 3092947 B2 20000925; JP H11504040 A 19990406

DOCDB simple family (application)

US 9620004 W 19961210; AU 1291997 A 19961210; CA 2240115 A 19961210; EP 96943763 A 19961210; JP 2000143459 A 20000516; JP 52225197 A 19961210