EP 0868515 A1 19981007 - COMPONENT OF A STAPHYLOCOCCUS SIGNAL TRANSDUCTION SYSTEM
Title (en)
COMPONENT OF A STAPHYLOCOCCUS SIGNAL TRANSDUCTION SYSTEM
Title (de)
KOMPONENTE EINES SIGNALÜBERTRAGUNGSSYSTEMS VON STAPHYLOCOCCUS.
Title (fr)
COMPOSANTE D'UN SYSTEME DE TRANSDUCTION DE SIGNAL PROVENANT DE STAPHYLOCOCCUS
Publication
Application
Priority
- GB 9603204 W 19961220
- GB 9526355 A 19951222
Abstract (en)
[origin: WO9723621A1] Novel response regulator polypeptides from Staphylococcus aureus WCUH29 having homology with the Bacillus subtilis degU product, and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polynucleotides and polypeptides for the treatment of infection, particularly bacterial infections. Antagonists against such polypeptides of the invention and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of the nucleic acid sequences and the polypeptides of the invention in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding response regulators and for detecting the polypeptide in a host.
IPC 1-7
C12N 15/31; C07K 14/31; A61K 39/085; G01N 33/50; C12Q 1/68; C07K 16/12
IPC 8 full level
G01N 33/53 (2006.01); A61K 39/085 (2006.01); C07K 14/195 (2006.01); C07K 14/31 (2006.01); C07K 16/12 (2006.01); C12N 1/21 (2006.01); C12N 15/00 (2006.01); C12N 15/02 (2006.01); C12N 15/09 (2006.01); C12N 15/31 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); A61K 39/00 (2006.01); C12R 1/445 (2006.01)
CPC (source: EP)
C07K 14/31 (2013.01); A61K 39/00 (2013.01); A61K 2039/51 (2013.01); C07K 2319/00 (2013.01)
Designated contracting state (EPC)
BE CH DE DK FR GB IT LI NL
DOCDB simple family (publication)
WO 9723621 A1 19970703; EP 0868515 A1 19981007; GB 9526355 D0 19960221; JP 2000503529 A 20000328
DOCDB simple family (application)
GB 9603204 W 19961220; EP 96943225 A 19961220; GB 9526355 A 19951222; JP 52342497 A 19961220