EP 0868516 A1 19981007 - NOVEL TCTS RESPONSE REGULATOR OF STAPHYLOCOCCUS AUREUS
Title (en)
NOVEL TCTS RESPONSE REGULATOR OF STAPHYLOCOCCUS AUREUS
Title (de)
Regulator der TCTS-Antwort aus Staphylococcus aureus
Title (fr)
NOUVEAU REGULATEUR DE REACTION DE SYSTEME DE TRANSDUCTION DE SIGNAL A DEUX COMPOSANTES (TCTS) DE STAPHYLOCOQUE DORE
Publication
Application
Priority
- GB 9603206 W 19961220
- GB 9526360 A 19951222
Abstract (en)
[origin: WO9723622A1] Novel response regulator polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polynucleotides and polypeptides for the treatment of infection, particularly bacterial infections. Antagonists against such polypeptides of the invention and their use as a therapeutic to treat infections, particularly bacterial infections, are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of the nucleic acid sequences and the polypeptides of the invention in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding response regulators and for detecting the polypeptide in a host.
IPC 1-7
C12N 15/31; C07K 14/31; A61K 39/085; C07K 16/12; G01N 33/50; C12Q 1/68
IPC 8 full level
C12N 15/02 (2006.01); A61K 31/00 (2006.01); A61K 38/00 (2006.01); A61K 39/085 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); C07K 14/195 (2006.01); C07K 14/31 (2006.01); C07K 16/12 (2006.01); C12N 1/21 (2006.01); C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12N 15/31 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); C12R 1/445 (2006.01)
CPC (source: EP US)
A61P 31/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); C07K 14/31 (2013.01 - EP US); A61K 2039/51 (2013.01 - EP US); C07K 2319/00 (2013.01 - EP US)
Citation (search report)
See references of WO 9723622A1
Designated contracting state (EPC)
BE CH DE DK FR GB IT LI NL
DOCDB simple family (publication)
WO 9723622 A1 19970703; EP 0868516 A1 19981007; GB 9526360 D0 19960221; JP 2000507088 A 20000613; US 6136556 A 20001024
DOCDB simple family (application)
GB 9603206 W 19961220; EP 96943227 A 19961220; GB 9526360 A 19951222; JP 52342697 A 19961220; US 77132196 A 19961220