Global Patent Index - EP 0870040 A2

EP 0870040 A2 19981014 - GENE DELIVERY VEHICLE-TARGETING LIGANDS

Title (en)

GENE DELIVERY VEHICLE-TARGETING LIGANDS

Title (de)

GENABGABEVEHIKEL-ZIELGERICHTETE LIGANDE

Title (fr)

LIGANDS DE CIBLAGE DE VEHICULES POUR L'APPORT DE GENES

Publication

EP 0870040 A2 19981014 (EN)

Application

EP 96945228 A 19961220

Priority

  • US 9620295 W 19961220
  • US 58054195 A 19951229
  • US 941195 P 19951229

Abstract (en)

[origin: WO9724446A2] Fusion proteins composed of an MHC Class I molecule, MHC Class II molecule, or beta 2 microglobulin, and a targeting ligand are disclosed. Also disclosed are nucleic acid molecules which encode such fusion proteins as well as suitable expression cassettes and host cells. Also provided are methods for targeting a gene delivery vehicle to a selected cell type utilizing gene delivery vehicles which contain on their surfaces one of the above-mentioned fusion proteins.

IPC 1-7

C12N 15/62; C12N 15/86; C12N 1/21; C07K 19/00

IPC 8 full level

C07K 14/05 (2006.01); C07K 14/505 (2006.01); C07K 14/74 (2006.01); C07K 16/28 (2006.01); C12N 1/21 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)

CPC (source: EP)

C07K 14/005 (2013.01); C07K 14/505 (2013.01); C07K 14/70539 (2013.01); C07K 16/2881 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01); C12N 2710/16222 (2013.01); C12N 2740/13043 (2013.01)

Citation (search report)

See references of WO 9724446A2

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB IE IT LI LU NL SE

DOCDB simple family (publication)

WO 9724446 A2 19970710; WO 9724446 A3 19971023; EP 0870040 A2 19981014

DOCDB simple family (application)

US 9620295 W 19961220; EP 96945228 A 19961220