Global Patent Index - EP 0871441 B1

EP 0871441 B1 20030813 - DFMO AND TAXOL FOR THE TREATMENT OR PREVENTION OF BREAST CANCER

Title (en)

DFMO AND TAXOL FOR THE TREATMENT OR PREVENTION OF BREAST CANCER

Title (de)

DFMO und Taxol zur Behandlung bzw. Vorbeugung von Brustkrebs

Title (fr)

DFMO ET TAXOL POUR LE TRAITEMENT OU LA PREVENTION DU CANCER DU SEIN

Publication

EP 0871441 B1 20030813 (EN)

Application

EP 97910042 A 19971003

Priority

  • US 9718252 W 19971003
  • US 2783796 P 19961004

Abstract (en)

[origin: WO9814188A1] Preparations comprising a single enantiomer or defined ratio of enantiomers of alphadifluoromethylornithine (DFMO) are provided for treating, preventing, controlling the growth of and/or reducing the risk of developing estrogen independent breast cancer or tumor. The preparations containing a single DFMO enantiomer or defined nonracemic ratio of DFMO enantiomers will provide an enhanced pharmacological activity relative to a preparation comprising racemic DFMO. Methods for treating a patient having estrogen independent breast cancer, which methods comprise administering DFMO alone or in combination with taxol, are also provided.

IPC 1-7

A61K 31/335; A61K 31/195; A61P 35/00

IPC 8 full level

A61K 31/198 (2006.01); A61K 31/335 (2006.01)

CPC (source: EP)

A61K 31/198 (2013.01); A61K 31/335 (2013.01); A61P 35/00 (2017.12)

C-Set (source: EP)

A61K 31/335 + A61K 2300/00

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9814188 A1 19980409; AT E246923 T1 20030815; AU 4751597 A 19980424; DE 69724095 D1 20030918; DE 69724095 T2 20040527; EP 0871441 A1 19981021; EP 0871441 B1 20030813; ES 2205188 T3 20040501

DOCDB simple family (application)

US 9718252 W 19971003; AT 97910042 T 19971003; AU 4751597 A 19971003; DE 69724095 T 19971003; EP 97910042 A 19971003; ES 97910042 T 19971003