EP 0871449 A1 19981021 - HYDROXYNONYLADENINE ANALOGS WITH ENHANCED LIPOPHILIC AND ANTI-ISCHEMIC TRAITS
Title (en)
HYDROXYNONYLADENINE ANALOGS WITH ENHANCED LIPOPHILIC AND ANTI-ISCHEMIC TRAITS
Title (de)
HYDROXYNONYLADENIN ANALOGE MIT VERBESSERTEN LIPOPHILEN UND ANTIISCHÄMISCHEN EIGENSCHAFTEN
Title (fr)
ANALOGUES D'ERYTHRO-HYDROXYNONYLADENINE A PROPRIETES LIPOPHILES ET ANTI-ISCHEMIQUES RENFORCEES
Publication
Application
Priority
- CA 2199615 A 19960212
- US 9601990 W 19960212
Abstract (en)
[origin: WO9728803A1] Analogs of erythro-hydroxynonyladenine (EHNA) are disclosed which have been modified by bonding various types of moieties to the #8 or #9 carbon atoms in the "side chain" portion of the molecule. The compounds inhibit the intracellular enzymatic activity of adenosine deaminase and are therapeutically effective in reducing hypoxic and ischemic damage in heart and brain tissue.
IPC 1-7
IPC 8 full level
A61K 31/52 (2006.01)
CPC (source: EP)
A61K 31/52 (2013.01)
Designated contracting state (EPC)
AT BE CH DE ES FR GB IT LI NL SE
DOCDB simple family (publication)
WO 9728803 A1 19970814; AU 5522996 A 19970828; CA 2199615 A1 19970814; EP 0871449 A1 19981021; EP 0871449 A4 19981021
DOCDB simple family (application)
US 9601990 W 19960212; AU 5522996 A 19960212; CA 2199615 A 19960212; EP 96912400 A 19960212