Global Patent Index - EP 0871668 A4

EP 0871668 A4 2000-01-05 - HUMAN G-PROTEIN RECEPTOR HIBEF51

Title (en)

HUMAN G-PROTEIN RECEPTOR HIBEF51

Title (de)

MENSCHLICHER G-PROTEIN REZEPTOR HIBEF51

Title (fr)

HIBEF51, RECEPTEUR DE PROTEINES G HUMAINES

Publication

EP 0871668 A4 (EN)

Application

EP 95922244 A

Priority

  • CA 2221616 A
  • US 9507225 W

Abstract (en)

[origin: WO9639441A1] Human G-protein coupled receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the receptor nucleic acid sequences and detecting a level of the soluble form of the receptors in a sample derived from a host.

IPC 1-7

C07K 14/705; C12N 15/12

IPC 8 full level

C07K 14/705 (2006.01); C07K 14/72 (2006.01); C12N 15/12 (2006.01); A61K 38/00 (2006.01)

CPC

C07K 14/723 (2013.01); A61K 38/00 (2013.01); C12N 2799/026 (2013.01)

Citation (search report)

  • [YA] WO 9405695 A1 19940317 - UNIV NEW YORK [US]
  • [Y] WO 9307294 A1 19930415 - US HEALTH [US]
  • [Y] WO 9312134 A1 19930624 - HARVARD COLLEGE [US]
  • [AD] WO 9201810 A1 19920206 - LERNER MICHAEL R [US], et al
  • [A] EP 0590721 A1 19940406 - ENICHEM SPA [IT]
  • [XY] DATABASE STN CABA 1 January 1900 (1900-01-01), XP002121341, Database accession no. R17870 & DATABASE SWISSPROT 1 January 1900 (1900-01-01), XP002121779, Database accession no. P04274
  • [X] DATABASE STN CABA 1 January 1900 (1900-01-01), XP002121342, Database accession no. R43119
  • [A] OLIVEIRA L. ET AL.: "A common motif in G-protein-coupled seven transmembrane helix receptors", JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, vol. 7, no. 6, 1 December 1993 (1993-12-01), pages 649 - 658, XP002050853, ISSN: 0920-654X
  • [A] LEE N.H. AND KERLAVAGE A.R.: "Molecular biology of G-protein-coupled receptors", DRUG NEWS AND PERSPECTIVES, vol. 6, no. 7, 1 September 1993 (1993-09-01), pages 488 - 497, XP000677175, ISSN: 0214-0934
  • See also references of WO 9639441A1

DCS

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family

WO 9639441 A1 19961212; AU 2699795 A 19961224; CA 2221616 A1 19961212; EP 0871668 A1 19981021; EP 0871668 A4 20000105