Global Patent Index - EP 0871706 A1

EP 0871706 A1 19981021 - STABILIZATION OF BLOOD PLATELETS AGAINST LOW TEMPERATURE ACTIVATION

Title (en)

STABILIZATION OF BLOOD PLATELETS AGAINST LOW TEMPERATURE ACTIVATION

Title (de)

STABILISATION VON BLUTPLÄTTCHEN GEGEN AKTIVIERUNG DURCH NIEDRIGE TEMPERATUR

Title (fr)

STABILISATION DES PLAQUETTES SANGUINES VIS-A-VIS DE L'ACTIVATION A BASSE TEMPERATURE

Publication

EP 0871706 A1 19981021 (EN)

Application

EP 95944344 A 19951218

Priority

  • US 9516519 W 19951218
  • US 36894195 A 19950105

Abstract (en)

[origin: WO9621001A1] Spontaneous activation of platelets at the low temperatures normally used for blood storage is reduced or eliminated by treating the platelets with thermal hysteresis proteins. Preferred thermal hysteresis proteins are antifreeze proteins and antifreeze glycoproteins from polar fish species, and chromatographic fractions Nos. 2-6 of antifreeze glycoproteins have been found to be particularly effective.

IPC 1-7

C12N 5/00; A61K 38/00; A61K 38/16; C07K 14/435

IPC 8 full level

C12N 5/07 (2010.01); A01N 1/00 (2006.01); A01N 1/02 (2006.01); A61K 35/14 (2006.01); A61K 35/19 (2015.01); A61M 1/36 (2006.01); C07K 14/46 (2006.01); C12N 5/071 (2010.01)

CPC (source: EP)

A01N 1/02 (2013.01); A01N 1/0221 (2013.01); A61K 35/19 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9621001 A1 19960711; AU 4641596 A 19960724; AU 696094 B2 19980903; CA 2207892 A1 19960711; CN 1220696 A 19990623; EP 0871706 A1 19981021; EP 0871706 A4 20010502; JP 2001513069 A 20010828

DOCDB simple family (application)

US 9516519 W 19951218; AU 4641596 A 19951218; CA 2207892 A 19951218; CN 95197246 A 19951218; EP 95944344 A 19951218; JP 52104996 A 19951218