EP 0873348 A4 20001108 - HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR 3
Title (en)
HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR 3
Title (de)
MENSCHLICHER VASKULARER ENDOTHELIALER WACHTUMSFAKTOR 3
Title (fr)
FACTEUR DE CROISSANCE 3 DE L'ENDOTHELIUM VASCULAIRE HUMAIN
Publication
Application
Priority
- CA 2224002 A 19950606
- US 9507283 W 19950606
Abstract (en)
[origin: WO9639421A1] Disclosed is a human VEGF3 polypeptide and DNA (RNA) encoding such VEGF3 polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques and antibodies and antagonist against such polypeptide. Also disclosed is a method of using such polypeptide for stimulating wound healing and for vascular tissue repair. Also provided are methods of using the antagonists to inhibit tumor growth, inflammation and to treat diabetic retinopathy, rheumatoid arthritis and psoriasis. Diagnostic methods for detecting mutations in the VEGF3 coding sequence and alterations in the concentration of VEGF3 protein in a sample derived from a host are also disclosed.
IPC 1-7
C12N 15/09; C12N 15/18; C12N 15/63; C12N 15/70; C12N 15/74; C12N 15/79; C12N 5/10; C12N 1/21; C07K 14/52; G01N 33/68; C12P 21/00; C07H 21/04
IPC 8 full level
C07K 14/52 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 14/52 (2013.01); A61K 38/00 (2013.01); C12N 2799/026 (2013.01)
Citation (search report)
- [E] WO 9627007 A1 19960906 - AMRAD OPERATIONS PTY LTD [AU], et al
- [E] WO 9626736 A1 19960906 - LUDWIG INST CANCER RES [US], et al
- See references of WO 9639421A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9639421 A1 19961212; CA 2224002 A1 19961212; EP 0873348 A1 19981028; EP 0873348 A4 20001108
DOCDB simple family (application)
US 9507283 W 19950606; CA 2224002 A 19950606; EP 95922260 A 19950606