EP 0873360 A4 20000621 - TRANSFORMING GROWTH FACTOR ALPHA HIII
Title (en)
TRANSFORMING GROWTH FACTOR ALPHA HIII
Title (de)
TRANSFORMIERENDER WACHSTUMSFAKTOR ALPHA HIII
Title (fr)
FACTEUR TRANSFORMANT DE CROISSANCE ALPHA HIII
Publication
Application
Priority
- CA 2242633 A 19960104
- US 9600149 W 19960104
Abstract (en)
[origin: WO9725349A1] The present invention discloses transforming growth factor alpha HIII polypeptides and polynucleotides encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides which include stimulating wound healing, treating neurological disorders, treating ocular disorders, treating kidney and liver disorders and stimulating embryogenesis and angiogenesis. Also disclosed are antagonists against such polypeptides and their use as a therapeutic to treat neoplasia. Also disclosed are diagnostic assays for detecting altered levels of the polypeptide of the present invention and mutations in the nucleic acid sequences which encode the polypeptides of the present invention.
IPC 1-7
IPC 8 full level
A61K 38/18 (2006.01); A61K 48/00 (2006.01); C07K 14/495 (2006.01); C12N 5/00 (2006.01); C12N 5/10 (2006.01); C12N 15/00 (2006.01); C12N 15/11 (2006.01); C12N 15/19 (2006.01); C12N 15/63 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 14/495 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [E] WO 9636709 A1 19961121 - HUMAN GENOME SCIENCES INC [US], et al
- [E] WO 9639497 A1 19961212 - HUMAN GENOME SCIENCES INC [US], et al
- [A] BARNARD J.A. ET AL.: "Auto- and cross-induction within the mammalian epidermal growth factor-related peptide family", J. BIOL. CHEM., vol. 269, no. 36, 9 September 1994 (1994-09-09), pages 22817 - 22822, XP002134363
- See references of WO 9725349A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9725349 A1 19970717; AU 4694696 A 19970801; CA 2242633 A1 19970717; EP 0873360 A1 19981028; EP 0873360 A4 20000621
DOCDB simple family (application)
US 9600149 W 19960104; AU 4694696 A 19960104; CA 2242633 A 19960104; EP 96902605 A 19960104