EP 0874833 A1 19981104 - 4,5-DIHYDRONAPHTH 1,2-C ISOXAZOLES AND DERIVATIVES THEREOF HAVING CNS ACTIVITY
Title (en)
4,5-DIHYDRONAPHTH 1,2-C ISOXAZOLES AND DERIVATIVES THEREOF HAVING CNS ACTIVITY
Title (de)
4,5-DIHYDRONAPHT(1,2-C)ISOXAZOLE UND DERIVATE DERSELBEN MIT ZNS-AKTIVITÄT
Title (fr)
4,5-DIHYDRONAPHTH 1,2-C ISOXAZOLES ET LEURS DERIVES AYANT UNE ACTIVITE AU NIVEAU DU SYSTEME NERVEUX CENTRAL
Publication
Application
Priority
- US 9619569 W 19961212
- US 58331996 A 19960105
Abstract (en)
[origin: WO9725317A1] 4,5-Dihydronaphth[1,2-c]isoxazole derivatives of general formula (I), where A, X and n are defined herein are disclosed. Such compounds are useful as serotonin 5-HT3 antagonists. These compounds are useful for the treatment of anxiety, psychiatric disorders, nausea, vomiting and drug dependency.
IPC 1-7
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/42 (2006.01); A61K 31/423 (2006.01); A61K 31/4375 (2006.01); A61K 31/46 (2006.01); A61K 31/496 (2006.01); A61P 1/00 (2006.01); A61P 1/08 (2006.01); A61P 25/04 (2006.01); A61P 25/18 (2006.01); A61P 25/22 (2006.01); A61P 25/30 (2006.01); A61P 43/00 (2006.01); C07D 261/20 (2006.01); C07D 413/04 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 451/06 (2006.01); C07D 453/02 (2006.01)
CPC (source: EP KR)
A61P 1/00 (2018.01 - EP); A61P 1/08 (2018.01 - EP); A61P 25/04 (2018.01 - EP); A61P 25/18 (2018.01 - EP); A61P 25/22 (2018.01 - EP); A61P 25/30 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 261/20 (2013.01 - EP KR); C07D 413/12 (2013.01 - EP KR); C07D 413/14 (2013.01 - EP KR); C07D 453/02 (2013.01 - EP KR)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated extension state (EPC)
AL LT LV RO SI
DOCDB simple family (publication)
WO 9725317 A1 19970717; AR 005347 A1 19990428; AU 1412697 A 19970801; AU 710059 B2 19990909; BR 9612578 A 19990727; CA 2241845 A1 19970717; CA 2241845 C 20021001; CN 1214046 A 19990414; EP 0874833 A1 19981104; HU P9903706 A2 20000828; HU P9903706 A3 20000928; IL 125197 A0 19990312; JP 3161737 B2 20010425; JP H11510816 A 19990921; KR 100308748 B1 20011212; KR 19990077033 A 19991025; NO 983100 D0 19980703; NO 983100 L 19980904; NZ 325587 A 19990225; ZA 9725 B 19970707
DOCDB simple family (application)
US 9619569 W 19961212; AR P970100015 A 19970103; AU 1412697 A 19961212; BR 9612578 A 19961212; CA 2241845 A 19961212; CN 96180175 A 19961212; EP 96944274 A 19961212; HU P9903706 A 19961212; IL 12519796 A 19961212; JP 52519797 A 19961212; KR 19980705166 A 19980704; NO 983100 A 19980703; NZ 32558796 A 19961212; ZA 9725 A 19970102