Global Patent Index - EP 0876355 A1

EP 0876355 A1 19981111 - 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION

Title (en)

2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION

Title (de)

2-THIOXO-IMIDAZOLIDIN-4-EINS DERIVATE UND IHRE VERWENDUNG ZUR ERHÖHUNG DER HDL-CHOLESTEROLKONZENTRATION

Title (fr)

DERIVES 2-THIOXO-IMIDAZOLIN-4-ONE ET LEUR UTILISATION POUR AUGMENTER LA CHOLESTEROLEMIE A LIPOPROTEINE DE HAUTE DENSITE

Publication

EP 0876355 A1 19981111 (EN)

Application

EP 96942118 A 19961125

Priority

  • US 9619164 W 19961125
  • US 56332595 A 19951128
  • US 765495 P 19951128
  • US 765895 P 19951128
  • US 766195 P 19951128
  • US 766595 P 19951128
  • US 766695 P 19951128

Abstract (en)

[origin: WO9719932A1] Compounds and a method for increasing the HDL cholesterol concentration in the blood of a mammal in need of increased HDL cholesterol blood concentration, which comprises administering to said mammal, orally or parenterally, a compound of formula (I) wherein R is alkyl; a substituted or unsubstituted aromatic N, O or S heterocycle; substituted or unsubstituted aryl, arylalkyl, benzhydryl or indanyl, in which the substituents are one to three members independently selected from the group consisting of alkyl, alkoxy, alkylthio, alkenyl, alkynyl, halo, perfluoroalkyl, perfluoroalkoxy or hydroxy; and R<1> is aryl, alkyl, alkenyl, alkynyl or substituted aryl where the substituents are one to three members independently selected from the group consisting of alkyl, alkoxy, alkylthio, alkenyl, alkynyl, halo, perfluoroalkyl, perfluoroalkoxy or hydroxy.

IPC 1-7

C07D 233/86; C07D 401/04; A61K 31/415

IPC 8 full level

A61K 31/00 (2006.01); A61K 31/415 (2006.01); A61K 31/4164 (2006.01); A61K 31/4166 (2006.01); A61K 31/4174 (2006.01); A61K 31/4439 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); C07D 233/86 (2006.01)

CPC (source: EP)

A61K 31/4166 (2013.01); A61K 31/4174 (2013.01); A61K 31/4439 (2013.01); A61P 9/00 (2017.12); A61P 9/10 (2017.12)

Citation (search report)

See references of WO 9719932A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9719932 A1 19970605; AU 1127697 A 19970619; CA 2238762 A1 19970605; EP 0876355 A1 19981111; JP 2000501100 A 20000202

DOCDB simple family (application)

US 9619164 W 19961125; AU 1127697 A 19961125; CA 2238762 A 19961125; EP 96942118 A 19961125; JP 52072497 A 19961125