EP 0877610 A4 19990915 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Title (en)
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Title (de)
INHIBITOREN DER FARNESYL-PROTEIN TRANSFERASE
Title (fr)
INHIBITEURS DE FARNESYL-PROTEINE TRANSFERASE
Publication
Application
Priority
- GB 9607124 A 19960404
- US 9701455 W 19970127
- US 1108196 P 19960130
Abstract (en)
[origin: WO9727853A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
IPC 1-7
A61K 31/415; C07D 233/54; C07D 233/60; C07D 233/61; C07D 233/66; C07D 233/90
IPC 8 full level
C07D 233/64 (2006.01); A61K 31/00 (2006.01); A61K 31/415 (2006.01); A61K 31/4164 (2006.01); A61K 31/4174 (2006.01); A61P 43/00 (2006.01); C07D 233/54 (2006.01); C07D 233/60 (2006.01); C07D 233/61 (2006.01); C07D 233/66 (2006.01); C07D 233/90 (2006.01)
CPC (source: EP)
A61K 31/4174 (2013.01); A61P 43/00 (2017.12); C07D 233/64 (2013.01)
Citation (search report)
- [A] EP 0236940 A2 19870916 - CIBA GEIGY AG [CH]
- See references of WO 9727853A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9727853 A1 19970807; AU 1952697 A 19970822; AU 703988 B2 19990401; EP 0877610 A1 19981118; EP 0877610 A4 19990915; JP 2000505797 A 20000516
DOCDB simple family (application)
US 9701455 W 19970127; AU 1952697 A 19970127; EP 97907546 A 19970127; JP 52780097 A 19970127