EP 0879237 A1 19981125 - ISOOXACEPHEM DERIVATIVES
Title (en)
ISOOXACEPHEM DERIVATIVES
Title (de)
ISOOXACEPHEM-DERIVATE
Title (fr)
DERIVES D'ISOOXACEPHEME
Publication
Application
Priority
- EP 97900972 A 19970109
- EP 9700057 W 19970109
- EP 96100538 A 19960116
Abstract (en)
[origin: WO9726260A1] The present invention relates to isooxacephem derivatives of general formula (I), wherein R<1> is hydrogen or an acyl group derived from a carboxylic acid; R<2> is hydrogen, hydroxy, lower alkyl, cycloalkyl, lower alkoxy, lower alkenyl, cycloalkenyl, lower alkynyl, aryl-lower alkyl, aryl, aryloxy, aryl-lower alkoxy or a heterocyclic ring; the lower alkyl, cycloalkyl, lower alkoxy, lower alkenyl, cycloalkenyl, lower alkynyl, aryl-lower alkyl, aryl, aryloxy, aryl-lower alkoxy and the heterocyclic ring being unsubstituted or substituted with at least one group selected from carboxy, amino, nitro, cyano, lower alkyl, lower alkoxy, hydroxy, halogen, -CONR<21>R<22>, -N(R<22>)COOR<23>, R<22>CO-, R<22>OCO- or R<22>COO-, wherein R<21> is hydrogen, lower alkyl, or cycloalkyl; R<22> is hydrogen or lower alkyl; R<23> is lower alkyl, lower alkenyl or a carboxylic acid protecting group; as well as readily hydrolyzable esters thereof, pharmaceutically acceptable salts of said compounds and hydrates of the compounds of formula (I) and of their esters and salts.
IPC 1-7
IPC 8 full level
C07D 507/04 (2006.01); A61K 31/00 (2006.01); A61K 31/535 (2006.01); A61K 31/5375 (2006.01); A61K 31/5383 (2006.01); A61P 31/00 (2006.01); C07D 498/04 (2006.01); C07D 507/06 (2006.01); C07D 507/08 (2006.01)
CPC (source: EP KR US)
A61P 31/00 (2017.12 - EP); C07D 498/04 (2013.01 - EP KR US); Y02P 20/55 (2015.11 - EP KR US)
Citation (search report)
See references of WO 9726260A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9726260 A1 19970724; AR 005454 A1 19990623; AU 1439997 A 19970811; AU 718495 B2 20000413; BR 9706980 A 19990406; CA 2242909 A1 19970724; CN 1208416 A 19990217; EP 0879237 A1 19981125; JP 2000503654 A 20000328; KR 19990077266 A 19991025; TR 199801366 T2 19981021; US 5811419 A 19980922
DOCDB simple family (application)
EP 9700057 W 19970109; AR P970100128 A 19970114; AU 1439997 A 19970109; BR 9706980 A 19970109; CA 2242909 A 19970109; CN 97191738 A 19970109; EP 97900972 A 19970109; JP 52564797 A 19970109; KR 19980705411 A 19980715; TR 9801366 T 19970109; US 76836996 A 19961217