EP 0879247 A4 20020130 - GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS
Title (en)
GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS
Title (de)
REZEPTOREN DES NEUROTROPHEN FAKTORS AUS GLIALZELLINIEN
Title (fr)
RECEPTEURS DU FACTEUR NEUROTROPHIQUE DERIVE DE LIGNEES DE CELLULES GLIALES
Publication
Application
Priority
- US 9618197 W 19961113
- US 661995 P 19951113
- US 1576796 P 19960416
- US 2063896 P 19960627
- US 2063996 P 19960627
- US 2196596 P 19960627
Abstract (en)
[origin: WO9718240A1] Receptors for Glial Cell Line-Derived Neurotrophic Factor (GDNF), their cellular expression, isolation, and biochemical characterization are disclosed. C-RET is disclosed as one receptor for GDNF; additional novel receptors are also disclosed. The preparation of monoclonal antibodies directed against GDNF is also disclosed.
IPC 1-7
IPC 8 full level
G01N 33/566 (2006.01); C07K 14/705 (2006.01); C07K 14/71 (2006.01); C12N 15/09 (2006.01); C12Q 1/02 (2006.01); G01N 30/88 (2006.01); G01N 30/90 (2006.01); G01N 33/15 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP KR)
C07K 14/705 (2013.01 - KR); C07K 14/71 (2013.01 - EP); G01N 33/566 (2013.01 - KR)
Citation (search report)
- [X] TRUPP M ET AL: "PERIPHERAL EXPRESSION AND BIOLOGICAL ACTIVITIES OF GDNF, A NEW NEUROTROPHIC FACTOR FOR AVIAN AND MAMMALIAN PERIPHERAL NEURONS", THE JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIVERSITY PRESS, US, vol. 130, no. 1, 1 July 1995 (1995-07-01), pages 137 - 148, XP002047358, ISSN: 0021-9525
- [X] TRUPP M ET AL: "Characterization of GDNF receptors on primary neurons and cell lines.", SOCIETY FOR NEUROSCIENCE ABSTRACTS, vol. 21, no. 1-3, 1995, 25th Annual Meeting of the Society for Neuroscience;San Diego, California, USA; November 11-16, 1995, pages 1302, XP001041846, ISSN: 0190-5295
- [PX] IBANEZ CARLOS F: "Biochemical characterisation of GDNF receptors and downstream responses.", INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, vol. 14, no. SUPPL. 1, 1996, 11th Biennial Meeting of the International Society for Developmental Neuroscience;Tampere, Finland; July 30-August 3, 1996, pages 76, XP001041850, ISSN: 0736-5748
- [PX] DURBEC P ET AL: "GDNF SIGNALLING THROUGH THE Ret RECEPTOR TYROSINE KINASE", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 381, 27 June 1996 (1996-06-27), pages 789 - 793, XP002092160, ISSN: 0028-0836
- [PX] TREANO J J S ET AL: "CHARACTERIZATION OF A MULTICOMPONENT RECEPTOR FOR GDNF", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 382, no. 6586, 4 July 1996 (1996-07-04), pages 80 - 83, XP002047616, ISSN: 0028-0836
- [PX] TRUPP M ET AL: "FUNCTIONAL RECEPTOR FOR GDNF ENCODED BY THE C-RET PROTO-ONCOGENE", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 381, 27 June 1996 (1996-06-27), pages 785 - 789, XP002071817, ISSN: 0028-0836
- See references of WO 9718240A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9718240 A1 19970522; AU 1158897 A 19970605; AU 718979 B2 20000504; CA 2237641 A1 19970522; EP 0879247 A1 19981125; EP 0879247 A4 20020130; JP 2000501924 A 20000222; KR 19990067508 A 19990825; NO 982141 D0 19980512; NO 982141 L 19980713; NZ 324511 A 19990929
DOCDB simple family (application)
US 9618197 W 19961113; AU 1158897 A 19961113; CA 2237641 A 19961113; EP 96942748 A 19961113; JP 51903997 A 19961113; KR 19980703530 A 19980512; NO 982141 A 19980512; NZ 32451196 A 19961113