Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

INHIBITOREN DER FARNESYL-PROTEIN TRANSFERASE

Title (fr)

INHIBITEURS DE LA FARNESYL-PROTEINE TRANSFERASE

Publication

EP 0880320 A4 19990616 (EN)

Application

EP 97904147 A 19970127

Priority

• GB 9605699 A 19960319
• US 9701599 W 19970127
• US 1086096 P 19960130

Abstract (en)

[origin: WO9727752A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7

A01N 47/28; A01N 61/00; A61K 31/00; A61K 31/17; A61K 31/41

IPC 8 full level

A61K 31/4164 (2006.01)

CPC (source: EP)

A61K 31/4164 (2013.01)

Citation (search report)

• [PX] WO 9639137 A1 19961212 - MERCK & CO INC [US], et al
• [E] WO 9736892 A1 19971009 - MERCK & CO INC [US], et al
• [E] WO 9736876 A1 19971009 - MERCK & CO INC [US], et al
• [E] WO 9736584 A1 19971009 - MERCK & CO INC [US], et al
• [E] WO 9736583 A1 19971009 - MERCK & CO INC [US], et al
• [E] WO 9727854 A1 19970807 - MERCK & CO INC [US], et al
• [E] WO 9727853 A1 19970807 - MERCK & CO INC [US], et al
• [E] WO 9727852 A1 19970807 - MERCK & CO INC [US], et al
• [E] WO 9718813 A1 19970529 - MERCK & CO INC [US], et al
• [PA] WO 9610034 A2 19960404 - MERCK & CO INC [US], et al
• See references of WO 9727752A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9727752 A1 19970807; AU 1851697 A 19970822; AU 712504 B2 19991111; CA 2243507 A1 19970807; EP 0880320 A1 19981202; EP 0880320 A4 19990616

DOCDB simple family (application)

US 9701599 W 19970127; AU 1851697 A 19970127; CA 2243507 A 19970127; EP 97904147 A 19970127