EP 0880601 A1 19981202 - PREDICTIVE ASSAY FOR THE OUTCOME OF IVF
Title (en)
PREDICTIVE ASSAY FOR THE OUTCOME OF IVF
Title (de)
TEST ZUR VORHERSAGE DES ERGEBNISSES VON IVF
Title (fr)
DOSAGE PREDICTIF POUR LE RESULTAT D'UNE FIV
Publication
Application
Priority
- GB 9700445 W 19970217
- GB 9603326 A 19960216
Abstract (en)
[origin: WO9730175A1] The present invention relates to assays (and kits) for predicting the chances of success of pregnancy using in vitro fertilisation (IVF) by determining the level of a modulator of 11 beta -hydroxysteroid dehydrogenase (11 beta -HSD) in a biological sample taken from a human female, for example in the environment of an oocyte, e.g. follicular fluid or granulosa cells. The amount of modulator (e.g. inhibitor) can be determined by reference to its effect on 11 beta -HSD activity and administration of a modulator (e.g. an 11 beta -HSD inhibitor) may increase the likelihood of pregnancy while 11 beta -HSD agonists may be potential contraceptive agents.
IPC 1-7
IPC 8 full level
C12Q 1/02 (2006.01); C12Q 1/32 (2006.01); G01N 33/573 (2006.01); G01N 33/74 (2006.01)
CPC (source: EP)
C12Q 1/32 (2013.01); G01N 2333/904 (2013.01)
Citation (search report)
See references of WO 9730175A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9730175 A1 19970821; EP 0880601 A1 19981202; GB 9603326 D0 19960417; JP 2000513208 A 20001010
DOCDB simple family (application)
GB 9700445 W 19970217; EP 97903495 A 19970217; GB 9603326 A 19960216; JP 52912697 A 19970217