Global Patent Index - EP 0881884 A4

EP 0881884 A4 20040714 - BACTERIAL DELIVERY SYSTEM

Title (en)

BACTERIAL DELIVERY SYSTEM

Title (de)

SYSTEM ZUR VERABREICHUNG VON BAKTERIEN

Title (fr)

SYSTEME D'APPORT BACTERIEN

Publication

EP 0881884 A4 20040714 (EN)

Application

EP 96932169 A 19960906

Priority

  • US 331895 P 19950906
  • US 52385595 A 19950906
  • US 1803596 P 19960521
  • US 9614190 W 19960906

Abstract (en)

[origin: WO9708955A1] This invention relates to a method of introducing functional nucleic acids into cells using a bacterial delivery system. The delivery system can be used as a vaccine to prevent or treat infectious diseases. This invention can be applied to any desired bacteria including attenuated strains of Shigella.

IPC 1-7

A01N 63/00; A61K 39/02; C12N 1/00; C12N 1/36

IPC 8 full level

G01N 33/569 (2006.01); A61K 35/74 (2006.01); A61K 39/02 (2006.01); A61K 39/112 (2006.01); A61K 48/00 (2006.01); C12N 1/21 (2006.01); C12N 9/04 (2006.01); C12N 15/09 (2006.01); C12N 15/85 (2006.01); A61K 39/00 (2006.01)

CPC (source: EP)

A61K 39/0283 (2013.01); C12N 15/85 (2013.01); A61K 2039/522 (2013.01); A61K 2039/53 (2013.01); Y02A 50/30 (2017.12)

Citation (search report)

  • [A] EP 0351322 A1 19900117 - PASTEUR INSTITUT [FR], et al
  • [X] PHALIPON A ET AL: "Live attenuated Shigella flexneri mutants as vaccine candidates against shigellosis and vectors for antigen delivery.", BIOLOGICALS : JOURNAL OF THE INTERNATIONAL ASSOCIATION OF BIOLOGICAL STANDARDIZATION. JUN 1995, vol. 23, no. 2, June 1995 (1995-06-01), pages 125 - 134, XP002280510, ISSN: 1045-1056
  • [DX] LINDBERG A A ET AL: "Development of an auxotrophic oral live Shigella flexneri vaccine.", VACCINE. APR 1988, vol. 6, no. 2, April 1988 (1988-04-01), pages 146 - 150, XP002280511, ISSN: 0264-410X
  • [X] MILLS S D ET AL: "ANALYSIS AND GENETIC MANIPULATION OF SHIGELLA VIRULENCE DETERMINANTS FOR VACCINE DEVELOPMENT", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 6, no. 2, 1 April 1988 (1988-04-01), pages 116 - 122, XP000051289, ISSN: 0264-410X
  • [A] HIGH N ET AL: "IpaB of Shigella flexneri causes entry into epithelial cells and escape from the phagocytic vacuole.", THE EMBO JOURNAL. MAY 1992, vol. 11, no. 5, May 1992 (1992-05-01), pages 1991 - 1999, XP000999368, ISSN: 0261-4189
  • [PX] SIZEMORE D R ET AL: "Attenuated Shigella as a DNA delivery vehicle for DNA-mediated immunization.", SCIENCE. 13 OCT 1995, vol. 270, no. 5234, 13 October 1995 (1995-10-13), pages 299 - 302, XP002071287, ISSN: 0036-8075
  • See references of WO 9708955A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9708955 A1 19970313; AU 7105996 A 19970327; AU 731061 B2 20010322; CA 2231332 A1 19970313; CA 2231332 C 20070417; EP 0881884 A1 19981209; EP 0881884 A4 20040714; IL 123569 A0 19981030; IL 123569 A 20061005; JP 2000500734 A 20000125

DOCDB simple family (application)

US 9614190 W 19960906; AU 7105996 A 19960906; CA 2231332 A 19960906; EP 96932169 A 19960906; IL 12356996 A 19960906; JP 51136197 A 19960906