EP 0882026 A1 19981209 - PROCESS FOR MAKING DIHYDROPYRIMIDINONES
Title (en)
PROCESS FOR MAKING DIHYDROPYRIMIDINONES
Title (de)
VERFAHREN ZUR HERSTELLUNG VON DIHYDROPYRIMIDONEN
Title (fr)
PROCEDE RELATIF A LA FABRICATION DE DIHYDROPYRIMIDINONES
Publication
Application
Priority
- GB 9617968 A 19960828
- US 9619651 W 19961212
- US 864195 P 19951214
Abstract (en)
[origin: WO9721687A1] The present invention provides a process for forming 5-(alkyl or alkoxy)carbonyl-6-alkyl-4-(aryl or alkyl)-3,4-2(1H)-dihydropyrimidinones by combining a beta -keto ester or diketone, an aldehyde and urea in the presence of a boron reagent, a metal salt (e.g., Cu2O) and a catalyst (e.g., acid). The reaction is typically run in one pot in a solvent to afford dihydropyrimidinones in higher yields and with easier work up than previously known methods.
IPC 1-7
IPC 8 full level
C07D 239/36 (2006.01); C07B 61/00 (2006.01); C07D 239/22 (2006.01)
CPC (source: EP KR)
C07D 239/22 (2013.01 - EP KR)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9721687 A1 19970619; AU 1331697 A 19970703; AU 705409 B2 19990520; BR 9611933 A 19990302; CA 2238924 A1 19970619; CZ 184098 A3 19981111; EP 0882026 A1 19981209; EP 0882026 A4 19990407; JP 2000501734 A 20000215; KR 19990072125 A 19990927; MX 9804766 A 19981031; NZ 326039 A 19990830; PL 327147 A1 19981123; SK 77398 A3 19990211
DOCDB simple family (application)
US 9619651 W 19961212; AU 1331697 A 19961212; BR 9611933 A 19961212; CA 2238924 A 19961212; CZ 184098 A 19961212; EP 96944785 A 19961212; JP 52216197 A 19961212; KR 19980704443 A 19980613; MX 9804766 A 19980612; NZ 32603996 A 19961212; PL 32714796 A 19961212; SK 77398 A 19961212