Global Patent Index - EP 0882703 A4

EP 0882703 A4 2000-08-02 - CYCLIC AMIC ACID DERIVATIVES

Title (en)

CYCLIC AMIC ACID DERIVATIVES

Title (de)

CYCLISCHE AMIC-SÄUREDERIVATE

Title (fr)

DERIVES D'ACIDES D'AMIDES CYCLIQUES

Publication

EP 0882703 A4 (EN)

Application

EP 97902605 A

Priority

  • JP 9700303 W
  • JP 4550096 A
  • JP 20667396 A

Abstract (en)

[origin: EP0882703A1] The present invention relates to a compound of the formula (I), or its pharmaceutically acceptable salt or ester: <CHEM> wherein Ar<1> is an aryl group or a heteroaromatic ring group; Ar is a group of the formula <CHEM> each of Ar<2> and Ar<3> is an aryl group or a heteroaromatic ring group; Cy is an aryl group, a heteroaromatic ring group or an aliphatic ring group which may contain one or two oxygen atoms; A<1> is a C1-4 chain hydrocarbon group; m is an integer of from 1 to 6; each of n and p is an integer of from 0 to 3; Q<1> is a single bond, a group of the formula -CH2O-, -OCH2-, -CH2S- or -SCH2-, or a C1-6 chain hydrocarbon group; Q<2> is a single bond or a group of the formula -(CH2)m- or -(CH2)n-W-(CH2)p-; Q<3> is a single bond, an oxygen atom, a sulfur atom, a methylene group, a vinylene group or a group of the formula -CO-, -NH-, -COO-, -OCO-, -CH2CH2-, -OCH2-, -SCH2-, -CH2O-, -CH2S-, -NHCO- or -CONH-; R<1> is a lower alkyl group; each of R<2> and R<3> is a hydrogen atom, a hydroxyl group or a lower alkyl group; W is an oxygen atom, a sulfur atom, a vinylene group or an ethynylene group; x is an integer of from 0 to 2; and y is 0 or 1; and an antitumor agent containing it as an active ingredient and intermediates for the production thereof.

IPC 1-7 (main, further and additional classification)

C07C 233/01; A61K 31/27; A61K 31/33; A61K 31/335; A61K 31/34; C07C 237/42; C07D 307/68

IPC 8 full level (invention and additional information)

C07C 233/51 (2006.01); C07D 317/32 (2006.01)

CPC (invention and additional information)

C07C 233/51 (2013.01); C07D 317/32 (2013.01)

Citation (search report)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

EP 0882703 A1 19981209; EP 0882703 A4 20000802; EP 0882703 B1 20020814; AT 222234 T 20020815; AU 1619197 A 19970828; CA 2244695 A1 19970814; CA 2244695 C 20060103; DE 69714709 D1 20020919; DE 69714709 T2 20030410; US 6011174 A 20000104; WO 9729078 A1 19970814

INPADOC legal status


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- Free text: 7C 07C 237/42 A, 7A 61K 31/335 B, 7A 61K 31/33 B

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