EP 0885195 A1 19981223 - PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDINE DERIVATIVES
Title (en)
PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDINE DERIVATIVES
Title (de)
VERFAHREN ZUR HERSTELLUNG VON SUBSTITUIERTEN PYRIDIN-DERIVATEN
Title (fr)
PROCEDE DE PREPARATION DE DERIVES DE PYRIDINE SUBSTITUEE
Publication
Application
Priority
- EP 9700447 W 19970127
- GB 9602675 A 19960209
Abstract (en)
[origin: WO9729089A1] The invention relates to a novel process for the preparation of substituted pyridine derivatives of formula (I) or a salt thereof, in which: R<1> is hydrogen, benzyl or a group of formula (A): where n is 1 to 20 and R<5> is hydrogen, C1-6alkyl, C1-6alkoxy or trifluoromethyl; m is 0 to 5; R<8> and R<9> are independently hydrogen, halogen, CO2H, C1-6alkyl or C1-6alkoxy; and R<10> is a group CR<2>=CR<3>-R<4> or CHR<2>-CHR<3>-R<4> where R<2> and R<3> are independently hydrogen or C1-6alkyl and R<4> is cyano or CO2R<6> is hydrogen or C1-6alkyl, and starting from a compound of formula (II), in which m, R<1>, R<8> and R<9> are as defined in formula (I) and R<7> is a leaving group by palladium catalysed vinylic substitution reactions.
IPC 1-7
IPC 8 full level
B01J 31/24 (2006.01); C07D 213/65 (2006.01)
CPC (source: EP)
C07D 213/65 (2013.01)
Citation (search report)
See references of WO 9729089A1
Designated contracting state (EPC)
BE CH DE ES FR GB IT LI NL
DOCDB simple family (publication)
WO 9729089 A1 19970814; EP 0885195 A1 19981223; GB 9602675 D0 19960410; JP 2000505427 A 20000509
DOCDB simple family (application)
EP 9700447 W 19970127; EP 97904364 A 19970127; GB 9602675 A 19960209; JP 52811997 A 19970127