EP 0886642 A1 19981230 - IMMUNE CELL CYTOKINE
Title (en)
IMMUNE CELL CYTOKINE
Title (de)
IMMUNZELLENCYTOKIN
Title (fr)
CYTOKINE DE CELLULE IMMUNITAIRE
Publication
Application
Priority
- CA 2242964 A 19960111
- US 9600205 W 19960111
- US 78037097 A 19970109
Abstract (en)
[origin: WO9725338A1] Human Immune Cell Cytokine-like Hormone polypeptide and DNA (RNA) encoding such polypeptide in a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for stimulating the proliferation and differentiation of stem cells of the immune system. Antagonists against such polypeptides are also disclosed. The antagonists include antibodies which may be employed as a therapeutic to treat leukemia and lymphoblastoma, may also be used as imaging agents and diagnostic agents for detecting expression levels of the protein. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides.
IPC 1-7
C07H 21/00; C12N 1/21; C12N 5/10; C12N 15/63; C12P 21/02; C07K 1/00; C07K 14/52; C07K 16/24; C07K 17/00; A61K 31/395; A61K 38/19
IPC 8 full level
C07K 14/52 (2006.01); C07K 14/575 (2006.01); C12N 1/21 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
C07K 14/52 (2013.01); C07K 14/575 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C12N 2799/026 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9725338 A1 19970717; CA 2242964 A1 19970717; EP 0886642 A1 19981230; EP 0886642 A4 19990113
DOCDB simple family (application)
US 9600205 W 19960111; CA 2242964 A 19960111; EP 96902613 A 19960111