Global Patent Index - EP 0891335 A1

EP 0891335 A1 19990120 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

INHIBITOREN VON FARNESYLPROTEIN-TRANSFERASE

Title (fr)

INHIBITEURS DE TRANSFERASE DE FARNESYL-PROTEINE

Publication

EP 0891335 A1 19990120 (EN)

Application

EP 97917759 A 19970331

Priority

  • GB 9609334 A 19960503
  • US 9705295 W 19970331
  • US 1479496 P 19960403

Abstract (en)

[origin: WO9736877A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7

C07D 233/70; C07D 233/66; C07D 233/60; A61K 31/415

IPC 8 full level

C07D 233/64 (2006.01); A61K 31/00 (2006.01); A61K 31/415 (2006.01); A61K 31/4164 (2006.01); A61P 1/00 (2006.01); A61P 1/16 (2006.01); A61P 13/00 (2006.01); A61P 13/12 (2006.01); A61P 27/00 (2006.01); A61P 27/02 (2006.01); A61P 31/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); C07D 233/54 (2006.01); C07D 233/60 (2006.01); C07D 233/66 (2006.01); C07D 233/70 (2006.01); C07D 233/84 (2006.01); C07D 233/88 (2006.01)

CPC (source: EP)

A61P 1/00 (2017.12); A61P 1/16 (2017.12); A61P 13/00 (2017.12); A61P 13/12 (2017.12); A61P 27/00 (2017.12); A61P 27/02 (2017.12); A61P 31/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); C07D 233/64 (2013.01); C07D 233/84 (2013.01); C07D 233/88 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9736877 A1 19971009; AU 2600597 A 19971022; AU 707416 B2 19990708; CA 2250460 A1 19971009; EP 0891335 A1 19990120; EP 0891335 A4 20010816; JP 2000507589 A 20000620

DOCDB simple family (application)

US 9705295 W 19970331; AU 2600597 A 19970331; CA 2250460 A 19970331; EP 97917759 A 19970331; JP 53553197 A 19970331