EP 0891337 A1 19990120 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Title (en)
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Title (de)
INHIBITOREN DER FARNESYL-PROTEIN TRANSFERASE
Title (fr)
INHIBITEURS DE TRANSFERASE DE FARNESYL-PROTEINE
Publication
Application
Priority
- GB 9614316 A 19960708
- US 9705240 W 19970331
- US 1459496 P 19960403
Abstract (en)
[origin: WO9736879A1] The present invention is directed to substituted benzodiazepine compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
IPC 1-7
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/55 (2006.01); A61K 31/551 (2006.01); A61K 31/5513 (2006.01); A61P 13/00 (2006.01); A61P 13/12 (2006.01); A61P 27/00 (2006.01); A61P 27/02 (2006.01); A61P 31/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 243/24 (2006.01); C07D 403/12 (2006.01)
CPC (source: EP)
A61P 13/00 (2017.12); A61P 13/12 (2017.12); A61P 27/00 (2017.12); A61P 27/02 (2017.12); A61P 31/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 243/24 (2013.01)
Citation (search report)
See references of WO 9736879A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9736879 A1 19971009; AU 2555997 A 19971022; CA 2250203 A1 19971009; EP 0891337 A1 19990120; JP 2000507587 A 20000620
DOCDB simple family (application)
US 9705240 W 19970331; AU 2555997 A 19970331; CA 2250203 A 19970331; EP 97917131 A 19970331; JP 53551397 A 19970331