Global Patent Index - EP 0891351 A1

EP 0891351 A1 19990120 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

INHIBITOREN VON FARNESYLPROTEIN-TRANSFERASE

Title (fr)

INHIBITEURS DE TRANSFERASE DE FARNESYL-PROTEINE

Publication

EP 0891351 A1 19990120 (EN)

Application

EP 97920003 A 19970401

Priority

  • GB 9613462 A 19960627
  • GB 9617255 A 19960816
  • US 9705309 W 19970401
  • US 1459296 P 19960403
  • US 2258796 P 19960724

Abstract (en)

[origin: WO9736890A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7

C07D 403/00; C07D 405/00; C07D 213/22; A61K 31/505; A61K 31/44

IPC 8 full level

A61K 31/00 (2006.01); A61K 31/44 (2006.01); A61K 31/4427 (2006.01); A61K 31/4439 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61P 9/00 (2006.01); A61P 13/00 (2006.01); A61P 13/12 (2006.01); A61P 27/00 (2006.01); A61P 27/02 (2006.01); A61P 31/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 233/54 (2006.01); C07D 233/70 (2006.01); C07D 401/14 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 413/06 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01)

CPC (source: EP)

A61P 9/00 (2017.12); A61P 13/00 (2017.12); A61P 13/12 (2017.12); A61P 27/00 (2017.12); A61P 27/02 (2017.12); A61P 31/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 233/56 (2013.01); C07D 233/64 (2013.01); C07D 233/70 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); C07D 413/06 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01)

Citation (search report)

See references of WO 9736890A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9736890 A1 19971009; AU 2430397 A 19971022; AU 704792 B2 19990506; CA 2249605 A1 19971009; EP 0891351 A1 19990120; JP 2000507591 A 20000620

DOCDB simple family (application)

US 9705309 W 19970401; AU 2430397 A 19970401; CA 2249605 A 19970401; EP 97920003 A 19970401; JP 53553697 A 19970401