EP 0891351 A1 19990120 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Title (en)
INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Title (de)
INHIBITOREN VON FARNESYLPROTEIN-TRANSFERASE
Title (fr)
INHIBITEURS DE TRANSFERASE DE FARNESYL-PROTEINE
Publication
Application
Priority
- GB 9613462 A 19960627
- GB 9617255 A 19960816
- US 9705309 W 19970401
- US 1459296 P 19960403
- US 2258796 P 19960724
Abstract (en)
[origin: WO9736890A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
IPC 1-7
C07D 403/00; C07D 405/00; C07D 213/22; A61K 31/505; A61K 31/44
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/44 (2006.01); A61K 31/4427 (2006.01); A61K 31/4439 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61P 9/00 (2006.01); A61P 13/00 (2006.01); A61P 13/12 (2006.01); A61P 27/00 (2006.01); A61P 27/02 (2006.01); A61P 31/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 233/54 (2006.01); C07D 233/70 (2006.01); C07D 401/14 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 413/06 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 13/00 (2017.12); A61P 13/12 (2017.12); A61P 27/00 (2017.12); A61P 27/02 (2017.12); A61P 31/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 233/56 (2013.01); C07D 233/64 (2013.01); C07D 233/70 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); C07D 413/06 (2013.01); C07D 417/06 (2013.01); C07D 417/14 (2013.01)
Citation (search report)
See references of WO 9736890A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9736890 A1 19971009; AU 2430397 A 19971022; AU 704792 B2 19990506; CA 2249605 A1 19971009; EP 0891351 A1 19990120; JP 2000507591 A 20000620
DOCDB simple family (application)
US 9705309 W 19970401; AU 2430397 A 19970401; CA 2249605 A 19970401; EP 97920003 A 19970401; JP 53553697 A 19970401