Global Patent Index - EP 0892639 A4

EP 0892639 A4 19990609 - METHOD OF TREATING UNDESIRED UTERINE CONTRACTIONS USING OPTICALLY PURE R- OR RR-ISOMERS OF ADRENERGIC BETA-2 AGONISTS

Title (en)

METHOD OF TREATING UNDESIRED UTERINE CONTRACTIONS USING OPTICALLY PURE R- OR RR-ISOMERS OF ADRENERGIC BETA-2 AGONISTS

Title (de)

METHODE ZUR BEHANDLUNG UNERWÜNSCHTER UTERUSKONTRAKTIONEN UNTER VERWENDUNG VON OPTISCH REINEN R- ODER RR-ISOMEREN VON ADRENERGEN BETA-2-AGONISTEN

Title (fr)

PROCEDE DE TRAITEMENT DES CONTRACTIONS UTERINES INDESIRABLES PAR UTILISATION D'ISOMERES R OU RR OPTIQUEMENT PURS D'AGONISTES -g(b)-2 ADRENERGIQUES

Publication

EP 0892639 A4 19990609 (EN)

Application

EP 97905640 A 19970128

Priority

  • US 9701342 W 19970128
  • US 59298896 A 19960129
  • US 2299596 P 19960802

Abstract (en)

[origin: WO9726871A1] A method of preventing or inhibiting undesired uterine contractions in a female individual by administering a pure eutomer of an adrenergic beta-2 agonist which relaxes uterine smooth muscle, while eliminating side effects caused by the distomer. The method is particularly useful in treating both pregnant and non-pregnant subjects that have demonstrated a propensity for undesired uterine contractions, while reducing side effects in the patients and/or their fetuses, such as bronchial hyperreactivity, tremor, nervousness, shakiness, dizziness, increased appetite and cardiac tachycardia. Importantly, administration of a pure eutomer also eliminates undesired contractions of the uterine smooth muscle while avoiding the uterine hyperreactivity that has now been found to be induced by the S- or SS-isomers of beta-2 agonists.

IPC 1-7

A61K 31/195

IPC 8 full level

A61K 31/137 (2006.01); A61K 31/138 (2006.01)

CPC (source: EP)

A61K 31/137 (2013.01); A61K 31/138 (2013.01)

Citation (search report)

  • [Y] EP 0455155 A1 19911106 - BOEHRINGER INGELHEIM VETMED [DE]
  • [YX] EP 0043807 A2 19820113 - DRACO AB [SE]
  • [Y] WO 9216173 A1 19921001 - SEPRACOR INC [US]
  • [Y] BORGSTRÖM L. ET AL: "Relative absorption of the two enantiomers of terbutaline after duodenal administration", EUR. J. CLIN. PHARMACOL., vol. 38, no. 6, 1990, pages 621 - 624, XP002097503
  • See references of WO 9726871A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9726871 A1 19970731; AU 2247997 A 19970820; CA 2247953 A1 19970731; EP 0892639 A1 19990127; EP 0892639 A4 19990609

DOCDB simple family (application)

US 9701342 W 19970128; AU 2247997 A 19970128; CA 2247953 A 19970128; EP 97905640 A 19970128