EP 0898576 A1 19990303 - DEATH DOMAIN CONTAINING RECEPTORS
Title (en)
DEATH DOMAIN CONTAINING RECEPTORS
Title (de)
ZELLTODDOMÄNE ENTHALTENDE REZEPTOREN
Title (fr)
RECEPTEURS CONTENANT UN DOMAINE DE MORT CELLULAIRE
Publication
Application
Priority
- US 9616849 W 19961017
- US 1328596 P 19960312
Abstract (en)
[origin: CA2249182A1] The present invention relates to novel Death Domain Containing Receptor (DR3 and DR3-V1) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR3 and DR3-V1 proteins. DR3 and DR3-V1 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR3 and DR3-V1 activity.
IPC 1-7
IPC 8 full level
A61K 38/19 (2006.01); C07H 21/04 (2006.01); C07K 14/715 (2006.01); C07K 16/28 (2006.01); C12N 15/12 (2006.01); C12N 15/28 (2006.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
AU 1115197 A 19971001; CA 2249182 A1 19970918; EP 0898576 A1 19990303; EP 0898576 A4 19990407
DOCDB simple family (application)
AU 1115197 A 19961017; CA 2249182 A 19961017; EP 96941942 A 19961017