Global Patent Index - EP 0900086 A4

EP 0900086 A4 20000112 - ENHANCEMENT OF SLEEP WITH A GROWTH HORMONE SECRETAGOGUE

Title (en)

ENHANCEMENT OF SLEEP WITH A GROWTH HORMONE SECRETAGOGUE

Title (de)

VERBESSERUNG DES SCHLAFS MITTELS EINES DIE SEKRETION VON WACHSTUMSHORMONEN FÖRDERNDEN STOFFES

Title (fr)

STIMULATION DU SOMMEIL AVEC UN SECRETAGOGUE D'HORMONE DE CROISSANCE

Publication

EP 0900086 A4 20000112 (EN)

Application

EP 97924576 A 19970505

Priority

  • GB 9611002 A 19960524
  • US 9707516 W 19970505
  • US 1678796 P 19960507

Abstract (en)

[origin: WO9741879A1] A growth hormone secretagogue is useful, alone or in combination with other agents, for enhancing and improving the quality of sleep, in particular by increasing sleep efficiency and augmenting sleep maintenance.

IPC 1-7

A61K 38/00; A61K 31/44

IPC 8 full level

C07D 471/10 (2006.01); A61K 31/00 (2006.01); A61K 31/435 (2006.01); A61K 31/438 (2006.01); A61K 31/475 (2006.01); A61K 31/55 (2006.01); A61K 38/05 (2006.01); A61K 38/25 (2006.01); A61K 38/30 (2006.01); A61K 45/00 (2006.01); A61P 25/20 (2006.01); C07D 495/10 (2006.01)

CPC (source: EP)

A61K 31/438 (2013.01); A61K 31/475 (2013.01); A61K 31/55 (2013.01); A61K 38/05 (2013.01); A61K 38/25 (2013.01); A61K 38/30 (2013.01); A61P 25/20 (2017.12)

C-Set (source: EP)

  1. A61K 38/25 + A61K 2300/00
  2. A61K 38/30 + A61K 2300/00

Citation (search report)

  • [X] EP 0662481 A1 19950712 - MERCK & CO INC [US]
  • [PX] WO 9640105 A1 19961219 - ARCH DEV CORP [US]
  • [E] WO 9734604 A1 19970925 - MERCK & CO INC [US], et al
  • [A] BIOLOGICAL ABSTRACTS, vol. 1994, 1994, Philadelphia, PA, US; abstract no. 75188, M L HARTMAN ET AL.: "Normal control of growth hormone secretion" XP002122541 & HORMONE RESEARCH, vol. 40, no. 1-3, 1993, Basel, pages 37 - 47
  • [A] J TAKAHARA ET AL.: "Stimulatory effects of gamma-hydroxybutyric acid on growth hormone and prolactin release in humans", J CLIN. ENDOCRIN. METAB., vol. 44, no. 5, 1977, USA, pages 1014 - 1017, XP000600031
  • [A] J TAKAHARA ET AL.: "Inhibitory effects of substance P on the gamma-aminobutyric acid and gamma-hydroxybutyric acid-induced growth hormone and prolactin release in male rats", LIFE SCIENCES, vol. 29, no. 12, 1981, UK, pages 1229 - 1233, XP000600046
  • [A] M MAMELAK ET AL.: "The effects of gamma-hydroxybutyrate on sleep", BIOLOGICAL PSYCHIATRY, vol. 12, no. 2, 1977, USA, pages 273 - 288, XP000600034
  • [PX] DATABASE MEDLINE 1 January 1900 (1900-01-01), XP002122540, Database accession no. 96320058 & G COPINSCHI ET AL.: "Effects of a 7-day treatment with a novel, orally active, growth hormone secretagogue, MK-677,on 24-hour GH profiles, insulin-like growth factor I, amd adrenocortical function in normal young men", J. CLIN. ENDOCRINOL. METABOLISM, vol. 81, no. 8, August 1996 (1996-08-01), pages 2776 - 2782
  • See references of WO 9741879A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9741879 A1 19971113; AU 2996397 A 19971126; AU 711884 B2 19991021; CA 2253390 A1 19971113; EP 0900086 A1 19990310; EP 0900086 A4 20000112; JP 2000511885 A 20000912

DOCDB simple family (application)

US 9707516 W 19970505; AU 2996397 A 19970505; CA 2253390 A 19970505; EP 97924576 A 19970505; JP 54009197 A 19970505