EP 0900281 A1 19990310 - COMPOSITION FOR THE TRANSFECTION OF HIGHER EUCARYOTIC CELLS
Title (en)
COMPOSITION FOR THE TRANSFECTION OF HIGHER EUCARYOTIC CELLS
Title (de)
ZUSAMMENSETZUNG FÜR DIE TRANSFEKTION HÖHERER EUKARYOTISCHER ZELLEN
Title (fr)
COMPOSITION POUR LA TRANSFECTION DE CELLULES EUCARYOTES SUPERIEURES
Publication
Application
Priority
- DE 19605548 A 19960215
- EP 9700649 W 19970213
Abstract (en)
[origin: DE19605548A1] The invention concerns a composition for the transfection of higher eucaryotic cells. A complex of a nucleic acid to be expressed in the cell and a cationic lipid present in a suboptimal concentration for transfection contains one or a plurality of membrane-active acid peptides and optionally helper lipid(s). The ratio of the total number of positive charges to the total number of negative charges in the composition is between approximately 0 and approximately 3.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01); C12N 15/87 (2006.01)
CPC (source: EP)
A61K 9/1272 (2013.01); A61K 47/543 (2017.07); C12N 15/87 (2013.01)
Citation (search report)
See references of WO 9730170A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
DE 19605548 A1 19970904; CA 2246227 A1 19970821; EP 0900281 A1 19990310; JP 2000504579 A 20000418; MX 9805507 A 19981129; WO 9730170 A1 19970821
DOCDB simple family (application)
DE 19605548 A 19960215; CA 2246227 A 19970213; EP 9700649 W 19970213; EP 97904426 A 19970213; JP 52898497 A 19970213; MX 9805507 A 19980707