EP 0900384 A2 19990310 - NOVEL TREATMENT
Title (en)
NOVEL TREATMENT
Title (de)
VERFAHREN ZUM SCREENING VON VERBINDUNGEN
Title (fr)
NOUVEAU TRAITEMENT
Publication
Application
Priority
- EP 9702050 W 19970422
- GB 9608657 A 19960426
Abstract (en)
[origin: WO9741443A2] A method of screening compounds to identify those compounds which inhibit or otherwise modulate the cleavage of presenilin-1 (PS-1) comprising measuring the extent of cleavage of PS-1 into 18kDa and 28kDa species as compared with the extent of cleavage in the absence of test compound, compounds identified thereby and their use in therapy.
IPC 1-7
G01N 33/68; C07K 14/47; C12N 5/10; A61K 35/00; C07K 16/18; C12N 15/12; C12N 15/85
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/00 (2006.01); A61K 45/00 (2006.01); A61P 25/28 (2006.01); C07K 5/00 (2006.01); C07K 7/06 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C12N 5/10 (2006.01); C12P 21/02 (2006.01); C12Q 1/02 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
A61P 25/28 (2017.12); C07K 14/4711 (2013.01); G01N 33/6896 (2013.01); G01N 2333/4709 (2013.01); G01N 2500/00 (2013.01); G01N 2800/2821 (2013.01)
Citation (search report)
See references of WO 9741443A2
Designated contracting state (EPC)
BE CH DE DK FR GB IT LI NL
DOCDB simple family (publication)
WO 9741443 A2 19971106; WO 9741443 A3 19971211; EP 0900384 A2 19990310; GB 9608657 D0 19960703; JP 2000511408 A 20000905
DOCDB simple family (application)
EP 9702050 W 19970422; EP 97920740 A 19970422; GB 9608657 A 19960426; JP 53855297 A 19970422