Global Patent Index - EP 0901471 A4

EP 0901471 A4 19990825 - ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE

Title (en)

ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE

Title (de)

ANTAGONISTEN DES GONADOTROPIN-RELEASING-HORMONS

Title (fr)

ANTAGONISTES DE LA GONADOLIBERINE

Publication

EP 0901471 A4 19990825 (EN)

Application

EP 97926600 A 19970516

Priority

  • GB 9612084 A 19960610
  • US 9708479 W 19970516
  • US 1715096 P 19960520

Abstract (en)

[origin: WO9744321A1] There are disclosed compounds of formula (I) and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related conditions in both men and women.

IPC 1-7

C07D 213/22; C07D 215/227; C07D 401/12; A61K 31/47; A61K 31/55

IPC 8 full level

A61K 31/00 (2006.01); A61K 31/47 (2006.01); A61K 31/4704 (2006.01); A61K 31/4706 (2006.01); A61K 31/535 (2006.01); A61K 31/5375 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61P 5/24 (2006.01); A61P 43/00 (2006.01); C07D 215/22 (2006.01); C07D 215/36 (2006.01); C07D 215/46 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 413/12 (2006.01); C07D 453/02 (2006.01); C07D 471/08 (2006.01); C07F 7/12 (2006.01)

CPC (source: EP)

A61P 5/24 (2017.12); A61P 43/00 (2017.12); C07D 215/22 (2013.01); C07D 215/36 (2013.01); C07D 215/46 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 413/12 (2013.01); C07D 453/02 (2013.01); C07D 471/08 (2013.01)

Citation (search report)

  • [E] WO 9744339 A1 19971127 - MERCK & CO INC [US], et al
  • [A] WO 9503289 A1 19950202 - MERCK & CO INC [US], et al
  • [X] WO 9311115 A2 19930610 - MERCK SHARP & DOHME [GB]
  • [XP] CARLING, ROBERT W. ET AL: "4-Substituted-3-phenylquinolin-2(1H)-ones: Acidic and Nonacidic Glycine Site N-Methyl-D-aspartate Antagonists with in Vivo Activity", J. MED. CHEM. (1997), 40(5), 754-765 CODEN: JMCMAR;ISSN: 0022-2623, XP002105399
  • [X] CHEMICAL ABSTRACTS, vol. 73, no. 15, 12 October 1970, Columbus, Ohio, US; abstract no. 77020w, NISHIMURA, HARUKI ET AL: "Synthesis of 4-hydroxy-2(1H)-quinolone derivatives" XP002105401 & CHEMICAL ABSTRACTS 8TH COLLECTIVE FORMULA INDEX., COLUMBUS US, XP002105400 & YAKUGAKU ZASSHI (1970), 90(7), 818-28 CODEN: YKKZAJ
  • See references of WO 9744321A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9744321 A1 19971127; AU 3132297 A 19971209; AU 706818 B2 19990624; CA 2254768 A1 19971127; EP 0901471 A1 19990317; EP 0901471 A4 19990825; JP 2000511533 A 20000905

DOCDB simple family (application)

US 9708479 W 19970516; AU 3132297 A 19970516; CA 2254768 A 19970516; EP 97926600 A 19970516; JP 54263297 A 19970516