EP 0906015 A1 19990407 - LIVER RETENTION CLEARING AGENTS
Title (en)
LIVER RETENTION CLEARING AGENTS
Title (de)
MITTEL ZUR UNTERDRÜCKUNG VON RÜCKHALTEPROZESSEN IN DER LEBER
Title (fr)
AGENTS DE SUPPRESSION DE LA RETENTION HEPATIQUE
Publication
Application
Priority
- US 9709400 W 19970606
- US 66060396 A 19960606
Abstract (en)
[origin: WO9746099A1] Liver retention clearing agents (LRCAs) and the use thereof are discussed. LRCAs are composed of a hepatic clearance directing component which directs the biodistribution of a LRCA-containing construct to hepatic clearance; a binding component which mediates binding of the LRCA to a compound for which rapid hepatic clearance is desired; a liver retention component which diminishes access of binding component-containing metabolites to target sites; and a structural component to provide a scaffold for the other components.
IPC 1-7
IPC 8 full level
A01N 43/04 (2006.01); A61K 31/70 (2006.01); A61K 47/48 (2006.01); A61K 51/04 (2006.01)
CPC (source: EP)
A61K 47/6893 (2017.07); B82Y 5/00 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9746099 A1 19971211; CA 2257353 A1 19971211; EP 0906015 A1 19990407; EP 0906015 A4 20040512
DOCDB simple family (application)
US 9709400 W 19970606; CA 2257353 A 19970606; EP 97926844 A 19970606