EP 0906015 A4 20040512 - LIVER RETENTION CLEARING AGENTS
Title (en)
LIVER RETENTION CLEARING AGENTS
Title (de)
MITTEL ZUR UNTERDRÜCKUNG VON RÜCKHALTEPROZESSEN IN DER LEBER
Title (fr)
AGENTS DE SUPPRESSION DE LA RETENTION HEPATIQUE
Publication
Application
Priority
- US 9709400 W 19970606
- US 66060396 A 19960606
Abstract (en)
[origin: WO9746099A1] Liver retention clearing agents (LRCAs) and the use thereof are discussed. LRCAs are composed of a hepatic clearance directing component which directs the biodistribution of a LRCA-containing construct to hepatic clearance; a binding component which mediates binding of the LRCA to a compound for which rapid hepatic clearance is desired; a liver retention component which diminishes access of binding component-containing metabolites to target sites; and a structural component to provide a scaffold for the other components.
IPC 1-7
IPC 8 full level
A61K 47/48 (2006.01)
CPC (source: EP)
A61K 47/6893 (2017.07); B82Y 5/00 (2013.01)
Citation (search report)
- [X] WO 9515978 A1 19950615 - NEORX CORP [US]
- [DX] WO 9325240 A2 19931223 - NEORX CORP [US], et al
- [X] WO 9515770 A1 19950615 - NEORX CORP [US]
- [PX] WO 9617613 A1 19960613 - NEORX CORP [US]
- [E] WO 9746098 A1 19971211 - NEORX CORP [US]
- [X] HIRABAYASHI H ET AL: "Development and pharmacokinetics of galactosylated poly-L-glutamic acid as a biodegradable carrier for liver-specific drug delivery.", PHARMACEUTICAL RESEARCH. JUN 1996, vol. 13, no. 6, June 1996 (1996-06-01), pages 880 - 884, XP008028760, ISSN: 0724-8741
- See references of WO 9746099A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9746099 A1 19971211; CA 2257353 A1 19971211; EP 0906015 A1 19990407; EP 0906015 A4 20040512
DOCDB simple family (application)
US 9709400 W 19970606; CA 2257353 A 19970606; EP 97926844 A 19970606