Global Patent Index - EP 0906115 A1

EP 0906115 A1 19990407 - COMBINED USE OF GnRH AGONIST AND ANTAGONIST

Title (en)

COMBINED USE OF GnRH AGONIST AND ANTAGONIST

Title (de)

KOMBINIERTE ANWENDUNG VON GNRH AGONIST UND ANTAGONIST

Title (fr)

UTILISATION COMBINEE D'AGONISTE ET D'ANTAGONISTE DE GONADOLIBERINE

Publication

EP 0906115 A1 19990407 (EN)

Application

EP 97919703 A 19970425

Priority

  • JP 9701459 W 19970425
  • JP 10979096 A 19960430
  • JP 13887396 A 19960531

Abstract (en)

[origin: WO9740846A1] The present invention relates to a pharmaceutical comprising a luteinizing hormone releasing hormone agonist in combination with a luteinizing hormone releasing hormone antagonist. By using a luteinizing hormone releasing hormone agonist and a luteinizing hormone releasing hormone antagonist in combination, the transient exacerbation with elevation of serum testosterone and estrogen owing to the pituitary-gonadotropic action (acute action) manifested immediately following an initial dose of the luteinizing hormone releasing hormone agonist can be successfully obviated.

IPC 1-7

A61K 38/09

IPC 8 full level

A61K 38/09 (2006.01)

CPC (source: EP US)

A61K 38/09 (2013.01 - EP US)

C-Set (source: EP US)

A61K 38/09 + A61K 2300/00

Citation (search report)

See references of WO 9740846A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9740846 A1 19971106; AU 2407997 A 19971119; CA 2250908 A1 19971106; CA 2250908 C 20120313; EP 0906115 A1 19990407; US 6015789 A 20000118

DOCDB simple family (application)

JP 9701459 W 19970425; AU 2407997 A 19970425; CA 2250908 A 19970425; EP 97919703 A 19970425; US 89431797 A 19970814