EP 0906441 A1 19990407 - ANTITUMOUR CELLULAR COMPOSITIONS EXPRESSING AT LEAST THREE TRANSGENES

Title (en)

ANTITUMOUR CELLULAR COMPOSITIONS EXPRESSING AT LEAST THREE TRANSGENES

Title (de)

ANTITUMORZELLZUSAMMENSETZUNGEN, DIE AUF MINDESTENS DREI TRANSGENE EXPRIMIEREN

Title (fr)

COMPOSITIONS CELLULAIRES ANTITUMORALES EXPRIMANT AU MOINS TROIS TRANSGENES

Publication

EP 0906441 A1 19990407 (FR)

Application

EP 97916490 A 19970325

Priority

FR 9700521 W 19970325
FR 9610927 A 19960906
IB 9600439 W 19960325

Abstract (en)

[origin: WO9735995A1] A novel antitumour composition including a cell population capable of expressing at least three therapeutic genes, particularly immunostimulatory and/or cytotoxic genes, is disclosed. A packaging cell expressing interleukin-2 and a retroviral vector expressing the gamma-interferon and thymidine kinase genes of herpes simplex virus 1 (HSV-1), as well as the therapeutical use thereof for preventing and treating cancer, are also disclosed.

IPC 1-7

C12N 15/86; A61K 48/00; C07K 14/57; C07K 14/55; C12N 5/10; C12N 7/04; C07K 14/15

IPC 8 full level

C12N 15/09 (2006.01); A61K 31/00 (2006.01); A61K 31/52 (2006.01); A61K 31/522 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 38/21 (2006.01); A61K 38/46 (2006.01); A61K 48/00 (2006.01); A61P 35/00 (2006.01); C07K 14/15 (2006.01); C07K 14/53 (2006.01); C07K 14/535 (2006.01); C07K 14/54 (2006.01); C07K 14/55 (2006.01); C07K 14/555 (2006.01); C07K 14/57 (2006.01); C12N 5/10 (2006.01); C12N 7/04 (2006.01); C12N 15/867 (2006.01)

CPC (source: EP)

A61K 48/00 (2013.01); A61P 35/00 (2017.12); C07K 14/005 (2013.01); C07K 14/55 (2013.01); C07K 14/57 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12N 2740/13022 (2013.01); C12N 2740/13043 (2013.01); C12N 2740/13062 (2013.01); C12N 2840/20 (2013.01); C12N 2840/203 (2013.01)

Citation (search report)

See references of WO 9735995A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9735995 A1 19971002; AU 2511897 A 19971017; AU 729908 B2 20010215; CA 2250332 A1 19971002; EP 0906441 A1 19990407; JP 2000507260 A 20000613

DOCDB simple family (application)

FR 9700521 W 19970325; AU 2511897 A 19970325; CA 2250332 A 19970325; EP 97916490 A 19970325; JP 53408697 A 19970325