EP 0907637 A1 19990414 - PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS
Title (en)
PHENYLALAMINE DERIVATIVES AS INTEGRIN INHIBITORS
Title (de)
PHENYLALANIN-DERIVATE ALS INTEGRIN-INHIBITOREN
Title (fr)
DERIVES DE PHENYLALANINE UTILISES COMME INHIBITEURS DE L'INTEGRINE
Publication
Application
Priority
- DE 19625929 A 19960628
- DE 19654483 A 19961227
- EP 9703275 W 19970623
Abstract (en)
[origin: WO9800395A1] Compounds of formula (I) wherein X, Y, Z, R<1>, R<2>, R<3> and R<4> have the meaning stated in claim 1, with the proviso that at least one element chosen from the group X, Y, Z must be CH2, as well as their physiologically harmless salts, can be used as integrin inhibitors, particularly for prophylaxis and treatment of circulatory diseases, in case of thrombosis, heart infarct, coronary heart diseases, arteriosclerosis, osteoporosis, in pathological processes which are maintained or propagated by angiogenesis, and in tumor therapy.
IPC 1-7
C07C 311/06; C07C 311/14; C07C 311/19; C07D 231/40; C07D 233/88; C07D 235/30; C07D 257/06; C07D 277/46; A61K 31/195
IPC 8 full level
A61K 31/197 (2006.01); A61K 31/195 (2006.01); A61K 31/198 (2006.01); A61K 31/216 (2006.01); A61P 7/02 (2006.01); A61P 9/04 (2006.01); A61P 9/10 (2006.01); A61P 35/00 (2006.01); C07C 311/06 (2006.01); C07C 311/14 (2006.01); C07C 311/19 (2006.01); C07D 231/40 (2006.01); C07D 233/88 (2006.01); C07D 235/30 (2006.01); C07D 257/04 (2006.01); C07D 277/46 (2006.01)
CPC (source: EP KR)
A61K 31/195 (2013.01 - KR); A61P 7/02 (2017.12 - EP); A61P 9/04 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 35/00 (2017.12 - EP); C07C 311/06 (2013.01 - EP KR); C07C 311/14 (2013.01 - EP KR); C07C 311/19 (2013.01 - EP); C07D 231/40 (2013.01 - EP KR); C07D 233/88 (2013.01 - EP); C07D 235/30 (2013.01 - EP); C07D 257/04 (2013.01 - EP); C07D 277/46 (2013.01 - EP)
Citation (search report)
See references of WO 9800395A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9800395 A1 19980108; AU 3343097 A 19980121; CA 2259224 A1 19980108; CZ 424998 A3 19990317; EP 0907637 A1 19990414; JP 2000516575 A 20001212; KR 20000022190 A 20000425; NO 986090 D0 19981223; NO 986090 L 19981223; PL 330915 A1 19990607; SK 176898 A3 19990507
DOCDB simple family (application)
EP 9703275 W 19970623; AU 3343097 A 19970623; CA 2259224 A 19970623; CZ 424998 A 19970623; EP 97929258 A 19970623; JP 50381298 A 19970623; KR 19980710608 A 19981224; NO 986090 A 19981223; PL 33091597 A 19970623; SK 176898 A 19970623