EP 0909165 A1 19990421 - ORGANISED ASSEMBLIES CONTAINING ENTRAPPED NEGATIVELY CHARGED POLYELECTROLYTES
Title (en)
ORGANISED ASSEMBLIES CONTAINING ENTRAPPED NEGATIVELY CHARGED POLYELECTROLYTES
Title (de)
STRUKTURIERTE AGGREGATE, DIE EINGESCHLOSSENE NEGATIV GELADENE POLYELEKTROVOLYTENENTHALTEN
Title (fr)
SYSTEMES ORGANISES CONTENANT DES POLYELECTROLYTES PIEGES ET A CHARGE NEGATIVE
Publication
Application
Priority
- IE 9700044 W 19970701
- IE 960485 A 19960702
Abstract (en)
[origin: WO9800112A1] Organised assemblies of zwitterionic lipids and negatively charged polyelectrolytes formed from repeating monomer units, in which the polyelectrolyte is substantially uniformly distributed, are described. The assemblies can entrap the polyelectrolyte with an efficiency of the order of 70 % or greater and can, therefore, be used as an effective means for the delivery of active polyelectrolytes to eucaryotic and procaryotic cells. The negatively charged polyelectrolytes can be oligomers such as oligonucleotides, including anti-sense oligomers or polymers such as nucleic acids, polysaccharides and proteins with a net negative charge.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01)
CPC (source: EP)
A61K 9/127 (2013.01); A61K 9/1274 (2013.01)
Citation (search report)
See references of WO 9800112A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9800112 A1 19980108; AU 3187597 A 19980121; EP 0909165 A1 19990421; IE 960485 A1 19980114
DOCDB simple family (application)
IE 9700044 W 19970701; AU 3187597 A 19970701; EP 97927347 A 19970701; IE 960485 A 19960702